1, 2, 3-Triazoles as biomimetics in peptide science

N Agouram, EM El Hadrami, A Bentama - Molecules, 2021 - mdpi.com
Natural peptides are an important class of chemical mediators, essential for most vital
processes. What limits the potential of the use of peptides as drugs is their low bioavailability …

Design strategies and medicinal applications of metal-peptidic bioconjugates

SM Meier-Menches, A Casini - Bioconjugate Chemistry, 2020 - ACS Publications
The conjugation of metal-based scaffolds to peptides, proteins, or antibodies allows the
systemic targeting of these payloads to specific locations in the body, such as target …

New tailored substituted benzothiazole Schiff base Cu (II)/Zn (II) antitumor drug entities: effect of substituents on DNA binding profile, antimicrobial and cytotoxic …

S Zehra, M Shavez Khan, I Ahmad… - Journal of Biomolecular …, 2019 - Taylor & Francis
New tailored Cu (II) & Zn (II) metal-based antitumor drug entities were synthesized from
substituted benzothiazole o‒vanillin Schiff base ligands. The complexes were thoroughly …

Covalent attachment of [Ni (alkynyl-cyclam)] 2+ catalysts to glassy carbon electrodes

A Zhanaidarova, CE Moore, M Gembicky… - Chemical …, 2018 - pubs.rsc.org
Surface modification of glassy carbon electrodes (GCEs) with molecular electrocatalysts is
an important step towards developing more efficient heterogeneous CO2 reduction …

Nontoxic Metal–Cyclam Complexes, a New Class of Compounds with Potency against Drug-Resistant Mycobacterium tuberculosis

M Yu, G Nagalingam, S Ellis, E Martinez… - Journal of Medicinal …, 2016 - ACS Publications
Tuberculosis (TB) accounted for 1.5 million deaths in 2014, and new classes of anti-TB
drugs are required. We report a class of functionalized 1, 8-disubstituted cyclam derivatives …

Peptide-mediated vectorization of metal complexes: conjugation strategies and biomedical applications

M Soler, L Feliu, M Planas, X Ribas, M Costas - Dalton Transactions, 2016 - pubs.rsc.org
The rich chemical and structural versatility of transition metal complexes provides numerous
novel paths to be pursued in the design of molecules that exert particular chemical or …

The outer-coordination sphere: incorporating amino acids and peptides as ligands for homogeneous catalysts to mimic enzyme function

WJ Shaw - Catalysis Reviews, 2012 - Taylor & Francis
Great progress has been achieved in the field of homogeneous transition metal-based
catalysis; however, as a general rule these solution-based catalysts are still easily …

[HTML][HTML] Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids

M Yu, JKH Wong, C Tang, P Turner… - Beilstein Journal of …, 2015 - beilstein-journals.org
The effective and efficient removal of the BF 2 moiety from F-BODIPY derivatives has been
achieved using two common Brønsted acids; treatment with trifluoroacetic acid (TFA) or …

Synthesis and Evaluation of 1, 8‐Disubstituted‐Cyclam/Naphthalimide Conjugates as Probes for Metal Ions

JKH Wong, S Ast, M Yu, R Flehr, AJ Counsell… - …, 2016 - Wiley Online Library
Fluorescent molecular probes for metal ions have a raft of potential applications in chemistry
and biomedicine. We report the synthesis and photophysical characterisation of 1, 8 …

Metal complexes of amino acids and peptides

E Farkas, I Sóvágó - Amino acids, peptides and proteins, 2012 - books.google.com
This chapter deals with the most important results published on the synthesis, structures,
solution equilibria, reactivity and applications of the metal complexes of amino acids …