The human gastrointestinal tract is home to trillions of microbes. Gut microbial communities
have a significant regulatory role in the intestinal physiology, such as gut motility. Microbial …

Our understanding of human colonic motility, and autonomic reflexes that generate motor
patterns, has increased markedly through high-resolution manometry. Details of the motor …

Gastric peristalsis is critically dependent on an underlying electrical conduction system.
Recent years have witnessed substantial progress in clarifying the operations of this system …

Background High‐resolution colonic manometry gives an unprecedented window into motor
patterns of the human colon. Our objective was to characterize motor activities throughout …

Simultaneous pressure waves (SPWs) in manometry recordings of the human colon have
been associated with gas expulsion. Our hypothesis was that the SPW might be a critical …

Chronic symptoms of gastric dysfunction are common following gastric surgery, but the
mechanisms underlying these have remained poorly understood. Disturbances of foregut …

Gastrointestinal (GI) motility is regulated in part by electrophysiological events called slow
waves, which are generated by the interstitial cells of Cajal (ICC). Slow waves propagate by …

Background Bioelectrical slow waves are a coordinating mechanism of small intestine
motility, but extracellular human studies have been restricted to a limited number of sparse …

The gut is enmeshed by a number of cellular networks, but there is only a limited
understanding of how these networks generate the complex patterns of activity that drive gut …

Background Neurogenic bowel is a dysmotility disorder following spinal cord injury (SCI)
that negatively impacts quality of life, social integration, and physical health. Colonic transit …