Alginate formulations: current developments in the race for hydrogel-based cardiac regeneration

G Cattelan, A Guerrero Gerbolés, R Foresti… - … in bioengineering and …, 2020 - frontiersin.org
Cardiovascular diseases, including myocardial infarction (MI), represent the main worldwide
cause of mortality and morbidity. In this scenario, to contrast the irreversible damages …

Chemical engineering of cell therapy for heart diseases

Z Li, S Hu, K Cheng - Accounts of chemical research, 2019 - ACS Publications
Conspectus Cardiovascular disease (CVD) is a major health problem worldwide. Since
adult cardiomyocytes irreversibly withdraw from the cell cycle soon after birth, it is hard for …

An injectable chitosan/dextran/β-glycerophosphate hydrogel as cell delivery carrier for therapy of myocardial infarction

X Ke, M Li, X Wang, J Liang, X Wang, S Wu… - Carbohydrate …, 2020 - Elsevier
Acute myocardial infarction (MI) is a common cardiovascular disease with high mortality. In
this study, an injectable thermosensitive hydrogel of chitosan (CS)/dextran (DEX)/β …

Injectable hydrogel-based combination therapy for myocardial infarction: a systematic review and Meta-analysis of preclinical trials

H Gao, S Liu, S Qin, J Yang, T Yue, B Ye… - BMC Cardiovascular …, 2024 - Springer
Introduction This study evaluates the effectiveness of a combined regimen involving
injectable hydrogels for the treatment of experimental myocardial infarction. Patient …

Injectable hydrogels for improving cardiac cell therapy—in vivo evidence and translational challenges

C Hoeeg, A Dolatshahi-Pirouz, B Follin - Gels, 2021 - mdpi.com
Cell therapy has the potential to regenerate cardiac tissue and treat a variety of cardiac
diseases which are currently without effective treatment. This novel approach to treatment …

Adipose-derived stromal/stem cells from large animal models: from basic to applied science

J Bukowska, AZ Szóstek-Mioduchowska… - Stem Cell Reviews and …, 2021 - Springer
Adipose-derived stem cells (ASCs) isolated from domestic animals fulfill the qualitative
criteria of mesenchymal stem cells, including the capacity to differentiate along multiple …

Application of adipose-derived stem cells in ischemic heart disease: theory, potency, and advantage

W Xiao, J Shi - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Adipose-derived mesenchymal stem cells (ASCs) represent an innovative candidate to treat
ischemic heart disease (IHD) due to their abundance, renewable sources, minor …

Annexin A1-Loaded Alginate Hydrogel Promotes Cardiac Repair via Modulation of Macrophage Phenotypes after Myocardial Infarction

L Zhang, L Shao, J Li, Y Zhang… - ACS Biomaterials Science …, 2024 - ACS Publications
Myocardial infarction (MI) is associated with inflammatory reaction, which is a pivotal
component in MI pathogenesis. Moreover, excessive inflammation post-MI can lead to …

Nanozyme-enhanced mitophagy to improve the efficacy of mesenchymal stem cells in myocardial infarction therapy

Z Sun, T Mei, Y Xin, T Tan, M Mutailipu, L Zhang… - Applied Materials …, 2024 - Elsevier
Mesenchymal stem cell therapy has emerged as a promising approach for the treatment of
myocardial infarction. However, the challenge of low cell survival and retention post …

Neutrophil-derived apoptotic body membranes-fused exosomes targeting treatment for myocardial infarction

J Wang, J Li, G Su, Y Zhang, Z Wang… - Regenerative …, 2024 - academic.oup.com
Myocardial infarction (MI) poses a substantial threat to human health, prompting extensive
research into effective treatment modalities. Preclinical studies have demonstrated the …