Do Statins Affect Cognitive Health? A Narrative Review and Critical Analysis of the Evidence

R Kazibwe, R Rikhi, S Mirzai, NP Ashburn… - Current Atherosclerosis …, 2024 - Springer
Abstract Purpose of Review Statins are the first-line treatment for hypercholesterolemia and
play a key role in the prevention of cardiovascular disease (CVD). Current studies report …

Aerobic Exercise facilitates the Nuclear translocation of SREBP2 by activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP …

Z Hu, Y Yuan, Z Tong, M Liao, S Yuan, W Wu… - International Journal of …, 2023 - mdpi.com
Impaired cholesterol synthesizing ability is considered a risk factor for the development of
Alzheimer's disease (AD), as evidenced by reduced levels of key proteases in the brain that …

Naringin and Naringenin: Potential Multi-Target Agents for Alzheimer's Disease

J Lu, J Chen, S Li, G Pan, Y Ou, L Yuan, J Jiang… - Current Medical …, 2024 - Springer
Alzheimer's disease (AD) is one of the most common forms of neurodegenerative dementia.
The etiology of AD is multifactorial, and its complex pathophysiology involves tau and …

[HTML][HTML] STAREE-Mind Imaging Study: a randomised placebo-controlled trial of atorvastatin for prevention of cerebrovascular decline and neurodegeneration in older …

IH Harding, J Ryan, S Heritier, S Spark… - BMJ Neurology …, 2023 - ncbi.nlm.nih.gov
Methods Participants aged 70 years or older (n= 340) will be randomised to atorvastatin or
placebo. Comprehensive brain MRI assessment will be undertaken at baseline and up to 4 …

Sex Differences in the Association Between LDL/HDL with Cognitive Decline in Older Adults: National Health and Nutrition Examination Survey

J Wen, X Hao, Y Jia, B Wang, J Pang… - Journal of Alzheimer's …, 2024 - content.iospress.com
Background: Lipids have a significant impact on the development and functioning of the
nervous system, but the sex differences between the association of LDL/HDL, which reflects …

Amyloid-beta metabolism in age-related neurocardiovascular diseases

E Aivalioti, G Georgiopoulos, S Tual-Chalot… - European Heart …, 2024 - academic.oup.com
Epidemiological evidence suggests the presence of common risk factors for the
development and prognosis of both cardio-and cerebrovascular diseases, including stroke …

[HTML][HTML] Advantages and challenges of using arterial spin labelling MRI to monitor cerebral blood flow in multi-centre clinical trials of neurodegenerative disease …

L Jarutyte, J Petr, N Turner, PG Kehoe… - … -Cognition and Behavior, 2025 - Elsevier
Arterial spin labelling (ASL) enables non-invasive quantification of regional brain perfusion
using MRI. ASL was used in the Reducing Pathology in Alzheimer's Disease through …