Management of high-risk corneal transplantation

A Di Zazzo, A Kheirkhah, TB Abud, S Goyal… - Survey of …, 2017 - Elsevier
The cornea is the most commonly transplanted tissue in medicine. The main cause of
corneal graft failure is allograft rejection. The incidence of graft rejection depends on the …

Graft failure after penetrating keratoplasty

SE Wilson - Survey of ophthalmology, 1990 - Elsevier
Despite the improving results that have been noted with penetrating keratoplasty, graft
failure remains a significant problem. The causes of graft failure are quite varied. Primary …

Evaluation of topical cyclosporine for the treatment of dry eye disease

HD Perry, R Solomon, ED Donnenfeld… - Archives of …, 2008 - jamanetwork.com
Objective To evaluate the use of topical cyclosporine, 0.05%(Restasis; Allergan Inc, Irvine,
California), for the treatment of mild, moderate, and severe dry eye disease unresponsive to …

[HTML][HTML] Corneal xenotransplantation: Where are we standing?

CH Yoon, HJ Choi, MK Kim - Progress in retinal and eye research, 2021 - Elsevier
The search for alternatives to allotransplants is driven by the shortage of corneal donors and
is demanding because of the limitations of the alternatives. Indeed, current progress in …

Treatments for corneal neovascularization: a review

D Gupta, C Illingworth - Cornea, 2011 - journals.lww.com
Corneal neovascularization (CNV) may be a physiological response to various stimuli, but a
chronic and persistent upregulation of neoangiogenesis can result in pathological CNV …

[HTML][HTML] Corneal allograft rejection: immunopathogenesis to therapeutics

Y Qazi, P Hamrah - Journal of clinical & cellular immunology, 2013 - ncbi.nlm.nih.gov
Corneal transplantation is among the most successful solid organ transplants. However,
despite low rejection rates of grafts in the 'low-risk'setting, rejection can be as high as 70 …

The profile of repeated corneal transplantation

V Bersudsky, T Blum-Hareuveni, U Rehany, S Rumelt - Ophthalmology, 2001 - Elsevier
PURPOSE: To evaluate the primary indications for corneal transplantation in patients with
repeated keratoplasties, graft survival, the causes and risk factors for failure. SETTING …

Systemic cyclosporine in high-risk keratoplasty: short-versus long-term therapy

JC Hill - Ophthalmology, 1994 - Elsevier
Background: In high-risk keratoplasty, the failure rate from rejection is high, especially in the
early postoperative period. If rejection could be prevented during this period, then ultimately …

Tacrolimus (FK506) in the management of high-risk corneal and limbal grafts

CML Sloper, RJ Powell, HS Dua - Ophthalmology, 2001 - Elsevier
OBJECTIVE: To assess the efficacy and side effects of tacrolimus in the management of
patients with high-risk corneal and limbal grafts. DESIGN: Noncomparative case series …

A randomized, placebo-controlled trial of topical cyclosporin A in steroid-dependent atopic keratoconjunctivitis

M Hingorani, L Moodaley, VL Calder, RJ Buckley… - Ophthalmology, 1998 - Elsevier
OBJECTIVE: This study aimed to investigate the therapeutic effect of topical cyclosporin A
(CsA) 2% in maize oil as a steroid-sparing agent in steroid-dependent atopic …