CTNNB1, encoding the ß-catenin protein, is a key oncogene contributing to liver
carcinogenesis. Hepatocellular carcinoma (HCC) is the most common form of primary liver …

Over the past 2 decades, the adaptor protein transducin β-like 1 (TBL1X) and its homolog
TBL1XR1 have been shown to be upregulated in solid tumors and hematologic …

In this study, we aimed to investigate whether and how Golgi phosphoprotein 3 (GOLPH3)
facilitates colon cancer metastasis via the regulation of autophagy and epithelial …

Metastasis is the main cause of death in patients with nasopharyngeal carcinoma (NPC).
The molecular mechanisms underlying the metastasis of NPC remain to be elucidated …

Despite recent advances in cancer immunotherapy, their efficacy for treating patients with
prostate adenocarcinoma (PRAD) is low due to complex immune evasion mechanisms …

Etoposide is a second-line chemotherapy agent widely used for metastatic colorectal
cancer. However, we discovered that etoposide treatment induced greater motility potential …

Transducin β-like protein 1 X-linked (TBL1X) is an essential scaffold protein involved in
multiple signaling pathways, such as the Wnt/β-catenin pathway, where it protects β-catenin …

The correct synthesis and degradation of proteins are vital for numerous biological
processes in the human body, with protein degradation primarily facilitated by the ubiquitin …

Targeted therapies are the mainstay of systemic therapies for patients with advanced,
unresectable, or metastatic hepatocellular carcinoma. Several therapeutic targets, such as c …

Background/Aim: B-cell lymphomas are characterized by diverse genetic anomalies
affecting B-cell differentiation. To expand targeted therapies, an in-depth grasp of the …