Acute appendicitis (AA) is among the most common cause of acute abdominal pain.
Diagnosis of AA is challenging; a variable combination of clinical signs and symptoms has …

Background For more than a century, appendicectomy has been the treatment of choice for
appendicitis. Recent trials have challenged this view. This study assessed the benefits and …

Unequivocal international guidelines regarding the diagnosis and management of patients
with acute appendicitis are lacking. The aim of the consensus meeting 2015 of the EAES …

Importance An increasing amount of evidence supports the use of antibiotics instead of
surgery for treating patients with uncomplicated acute appendicitis. Objective To compare …

Background Acute appendicitis (AA) is the most common surgical disease, and
appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key …

Importance Antibiotic therapy for acute uncomplicated appendicitis is effective in adult
patients, but its application in pediatric patients remains controversial. Objective To compare …

Objective To compare the safety and efficacy of antibiotic treatment versus appendicectomy
for the primary treatment of uncomplicated acute appendicitis. Design Meta-analysis of …

Procalcitonin (PCT) is used as a biomarker for the diagnosis of sepsis, severe sepsis and
septic shock. At the same time, PCT has also been used to guide antibiotic therapy. This …

Objectives: To assess the safety and efficacy of antibiotics treatment for suspected acute
uncomplicated appendicitis and to monitor the long term follow-up of non-operated patients …

Daniel LH Baird surgical registrar and research fellow1 2, Constantinos Simillis surgical
registrar1, Christos Kontovounisios locum consultant surgeon and honorary senior lecturer1 …