Shigella virulence protein VirG is a broadly protective antigen and vaccine candidate

G Desalegn, CS Tamilselvi, JM Lemme-Dumit… - npj Vaccines, 2024 - nature.com
Diarrhea caused by Shigella has been associated with high morbidity and mortality in young
children worldwide. There are no licensed vaccines, and those clinically advanced have …

Mapping the functional B-cell epitopes of Shigella invasion plasmid antigen D (IpaD)

S Li, W Zhang - Applied and Environmental Microbiology, 2024 - journals.asm.org
Shigella bacteria utilize the type III secretion system (T3SS) to invade host cells and
establish local infection. Invasion plasmid antigen D (IpaD), a component of Shigella T3SS …

A broad spectrum Shigella vaccine based on VirG53353 multiepitope region produced in a cell-free system

G Desalegn, C Abrahamson, K Ross Turbyfill… - npj Vaccines, 2025 - nature.com
Dysentery caused by Shigella species remains a major health threat to children in low-and
middle-income countries. There is no vaccine available. The most advanced candidates, ie …

A universal live vaccine platform against multiple serotypes Streptococcus suis based on polyvalent antigen protein

W Li, Y Li, S Wang, H Shi - Vaccine, 2025 - Elsevier
Streptococcus suis (S. suis) is a major pathogen that poses a long-term threat to swine
populations. Due to its foodborne transmission, this pathogen has recently emerged as a …

MecVax supplemented with CFA MEFA-II induces functional antibodies against 12 adhesins (CFA/I, CS1–CS7, CS12, CS14, CS17, and CS21) and 2 toxins (STa, LT) …

C Zhang, S Li, I Upadhyay, KL Lauder… - Microbiology …, 2024 - Am Soc Microbiol
Enterotoxigenic Escherichia coli (ETEC) strains that produce various adhesins and one or
two enterotoxins are the leading causes of children's diarrhea and travelers' diarrhea …