Binary polymeric amorphous carvedilol solid dispersions: In vitro and in vivo characterization

M Krstić, L Manić, N Martić, D Vasiljević… - European Journal of …, 2020 - Elsevier
Binary polymeric amorphous carvedilol solid dispersions were prepared using solvent
method by varying solvent type, polymer type and carvedilol to polymer ratio in order to …

Design and Development of A Commercially Viable In Situ Nanoemulgel for The Treatment of Postmenopausal Osteoporosis

F Zakir, A Ahmad, U Farooq, MA Mirza, A Tripathi… - …, 2020 - Taylor & Francis
Aim: To investigate the potential of a thermosensitive intranasal formulation of raloxifene
hydrochloride (RH) for systemic delivery with the possibility of enhanced bioavailability and …

Smart karaya-locust bean gum hydrogel particles for the treatment of hypertension: optimization by factorial design and pre-clinical evaluation

B Laha, R Goswami, S Maiti, KK Sen - Carbohydrate polymers, 2019 - Elsevier
This investigation was undertaken to unveil the controlled drug delivery and preclinical anti-
hypertensive potential of a novel interpenetrating biopolymer-based network of karaya gum …

Formulation by design of felodipine loaded liquid and solid self nanoemulsifying drug delivery systems using Box–Behnken design

S Verma, SK Singh, PRP Verma… - Drug development and …, 2014 - Taylor & Francis
Objective: To design and develop liquid and solid self-nanoemulsifying drug delivery
systems (SNEDDS and S-SNEDDS) of felodipine (FLD) using Box–Behnken design (BBD) …

Biopolymer-Capped Pyrazinamide-Loaded Colloidosomes: In Vitro Characterization and Bioavailability Studies

A Singh, SS Das, J Ruokolainen, KK Kesari… - ACS …, 2023 - ACS Publications
This study aimed to prepare colloidosome particles loaded with pyrazinamide (PZA). These
drug-loaded colloidosomes were prepared using an in situ gelation technique using a …

In silico-in vitro-in vivo studies of experimentally designed carvedilol loaded silk fibroin-casein nanoparticles using physiological based pharmacokinetic model

S Kumar, SK Singh - International journal of biological macromolecules, 2017 - Elsevier
The study aimed to design and develop carvedilol loaded silk fibroin-casein nanoparticles
using 3 2 full factorial design. Silk fibroin and casein concentration were selected as the …

[PDF][PDF] Formulation and Investigation of Lacidipine as a Nanoemulsions

RA Dahash, NA Rajab - Iraqi Journal of Pharmaceutical Sciences (P-ISSN …, 2020 - iasj.net
Lacidipine (LCDP) is a calcium-channel blocker with low aqueous solubility and
bioavailability. Nanoemulsion (NE) is one of the popular methods that has been used to …

Evaluation of carvedilol-loaded microsponges with nanometric pores using response surface methodology

R Saini, SK Singh, PRP Verma - Journal of Experimental …, 2014 - Taylor & Francis
This study demonstrates the use of factorial design for the preparation of microsponges of
carvedilol with nanometric pores using the response surface methodology and to establish …

Amorphous Form of Carvedilol Phosphate—The Case of Divergent Properties

S Sip, N Rosiak, A Miklaszewski, P Talarska, E Dudziec… - Molecules, 2021 - mdpi.com
The amorphous form of carvedilol phosphate (CVD) was obtained as a result of grinding.
The identity of the obtained amorphous form was confirmed by powder X-ray diffraction …

Co-rotating twin screw process for continuous manufacturing of solid crystal suspension: A promising strategy to enhance the solubility, permeation and oral …

PD Navti, G Fernandes, S Soman, AN Nikam… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background In the current work, co-rotating twin-screw processor (TSP) was utilized to
formulate solid crystal suspension (SCS) of carvedilol (CAR) for enhancing its solubility …