Acetaldehyde, the first product of ethanol metabolism, has been speculated to be involved in
many pharmacological and behavioral effects of ethanol. In particular, acetaldehyde has …

Acetaldehyde has long been suggested to be involved in a number of ethanol's
pharmacological and behavioral effects, such as its reinforcing, aversive, sedative, amnesic …

Tobacco use has one of the highest rates of addiction and relapse of any abused drug.
Paradoxically, however, in animal models of reinforcement nicotine appears weak …

This review evaluates the presumed contribution of acetaldehyde to tobacco smoke
addiction. In rodents, acetaldehyde induces reinforcing effects, and acts in concert with …

Mainly known for its more famous parent compound, ethanol, acetaldehyde was first studied
in the 1940s, but then research interest in this compound waned. However, in the last two …

After decades of uncertainties and drawbacks, the study on the role and significance of
acetaldehyde in the effects of ethanol seemed to have found its main paths. Accordingly, the …

Ethanol excites dopamine (DA) neurons in the posterior ventral tegmental area (pVTA). This
effect is responsible for ethanol's motivational properties and may contribute to alcoholism …

This paper reports, for the first time, on the analysis of ethanol (EtOH) and acetaldehyde
(AcH) concentrations in the blood and brains of Aldh2-knockout (Aldh2-KO) and C57B6/6J …

Acetaldehyde, the first product of ethanol metabolism, has been speculated to be involved in
many behavioral effects of ethanol. However, its precise role remains a matter of debate …

The possible involvement of salsolinol (Sal), an endogenous condensation product of ACD
(the first metabolite of ethanol) and dopamine, in the neurochemical basis underlying …