Systematic reviews represent a fundamental study design, providing the highest level of
evidence across diverse research inquiries, encompassing both public health and clinical …

Formulating a research question is a crucial step in directing any scientific study. The
classical evidence-based approach to formulating a question uses the PICO framework …

Excessive and improper use of antibiotics causes antimicrobial resistance which is a major
threat to global health security. Hospitals in sub-Saharan Africa (SSA) has the highest …

Methods MEDLINE, Embase, Web of Science and manual search of relevant papers since
1987 to February 2023 was searched. Random effects meta-analyses were performed. The …

With the abounding literature, a rigorous framework with concrete steps is needed for
synthesising the breadth, depth and accuracy of published knowledge. Systematic reviews …

Aim: This systematic review aimed to evaluate the influence of single-visit and multi-visit non-
surgical endodontic re-treatments on the incidence, intensity, and duration of postoperative …

Drug repurposing, also known as drug repositioning or drug reprofiling, is gaining
prominence as a strategic approach to addressing unmet medical needs. This review article …

Systematic reviews (SRs) are a way of synthesizing evidence from research and are
extensively used in health care to inform clinical practice, research, and policy. In contrast to …

This systematic review offers managers in large US organizations strategies to increase the
effectiveness of DEI program implementation. One of the goals of DEI programs is to …

Chronic kidney disease (CKD) is a public health challenge of major global concern, defined
by the progressive deterioration of kidney function and related complications. The …