Bat-borne virus diversity, spillover and emergence

M Letko, SN Seifert, KJ Olival, RK Plowright… - Nature Reviews …, 2020 - nature.com
Most viral pathogens in humans have animal origins and arose through cross-species
transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus …

Emerging concepts and technologies in vaccine development

M Brisse, SM Vrba, N Kirk, Y Liang, H Ly - Frontiers in immunology, 2020 - frontiersin.org
Despite the success of vaccination to greatly mitigate or eliminate threat of diseases caused
by pathogens, there are still known diseases and emerging pathogens for which the …

Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

[HTML][HTML] Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non …

PM Folegatti, M Bittaye, A Flaxman… - The Lancet Infectious …, 2020 - thelancet.com
Summary Background Cases of Middle East respiratory syndrome coronavirus (MERS-CoV)
infection continue to rise in the Arabian Peninsula 7 years after it was first described in Saudi …

Vaccine development: Current trends and technologies

R Poria, D Kala, R Nagraik, Y Dhir, S Dhir, B Singh… - Life Sciences, 2024 - Elsevier
Despite the effectiveness of vaccination in reducing or eradicating diseases caused by
pathogens, there remain certain diseases and emerging infections for which developing …

Effects of climate change on the occurrence and distribution of livestock diseases

B Bett, P Kiunga, J Gachohi, C Sindato… - Preventive veterinary …, 2017 - Elsevier
The planet's mean air and ocean temperatures have been rising over the last century
because of increasing greenhouse gas (GHG) emissions. These changes have substantial …

Rift Valley fever: biology and epidemiology

D Wright, J Kortekaas, TA Bowden… - Journal of General …, 2019 - microbiologyresearch.org
Rift Valley fever (RVF) is a mosquito-borne viral zoonosis that was first discovered in Kenya
in 1930 and is now endemic throughout multiple African countries and the Arabian …

[HTML][HTML] ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice

NK Alharbi, E Padron-Regalado, CP Thompson… - Vaccine, 2017 - Elsevier
Abstract The Middle East respiratory syndrome coronavirus (MERS-CoV) has infected more
than 1900 humans, since 2012. The syndrome ranges from asymptomatic and mild cases to …

The current and future state of vaccines, antivirals and gene therapies against emerging coronaviruses

LV Tse, RM Meganck, RL Graham… - Frontiers in microbiology, 2020 - frontiersin.org
Emerging coronaviruses (CoV) are constant global public health threats to society. Multiple
ongoing clinical trials for vaccines and antivirals against CoVs showcase the availability of …

Identification and immunogenicity of African swine fever virus antigens

CL Netherton, LC Goatley, AL Reis, R Portugal… - Frontiers in …, 2019 - frontiersin.org
African swine fever (ASF) is a lethal haemorrhagic disease of domestic pigs for which there
is no vaccine. Strains of the virus with reduced virulence can provide protection against …