Yeast cells are well adapted to interfacial habitats, such as the surfaces of soil or plants,
where they can resist frequent fluctuations between wet and dry conditions. Saccharomyces …

Solute–solvent interactions are key for the assembly and proper functioning of
biomacromolecules and play important roles in many fields of organic and polymer …

Genomic DNA base composition (GC content) is predicted to significantly affect genome
functioning and species ecology. Although several hypotheses have been put forward to …

Neutron crystallography allows direct determination of the proton and deuteron positions of
a macromolecule and its bound solvent. Key advances in neutron macromolecular …

Macromolecules in their environment--Macromolecules as physical particles--
Understanding macromolecular structures--Mass and charge--Structure function studies …

There is currently wide interest in room temperature storage of dehydrated DNA. However,
there is insufficient knowledge about its chemical and structural stability. Here, we show that …

Neutron scattering studies provide important information in structural biology that is not
accessible using other approaches. The uniqueness of the technique, and its …

Quadruplex DNAs can fold into a variety of distinct topologies, depending in part on loop
types and orientations of individual strands, as shown by high-resolution crystal and NMR …

We have made a detailed study of one of the most surprising sources of polymorphism in B-
DNA: the high twist/low twist (HT/LT) conformational change in the d (CpG) base pair step …

High-resolution crystal structures of the DNA duplex sequence d (CGCGAATTCGCG) 2
complexed with three minor-groove ligands are reported. A highly conserved cluster of 11 …