Background Exosomes are progressively known as significant mediators of cell-to-cell
communication. They convey active biomolecules to target cells and have vital functions in …

The field of cancer nanomedicine seeks to overcome the inherent shortcomings of
conventional cancer diagnostics and therapies. Yet despite the surge of interest in and …

Molecular imaging via afterglow luminescence minimizes tissue autofluorescence and
increases the signal-to-noise ratio. However, the induction of afterglow requires the prior …

Extracellular-vesicle-based cell-to-cell communication is conserved across all kingdoms of
life. There is compelling evidence that extracellular vesicles are involved in major (patho) …

Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

Nanoparticle-based systems imbued with both diagnostic and therapeutic functions, known
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …

In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …

Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Following its discovery more than 30 years ago, the enhanced permeability and retention
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …