Production of extracellular superoxide radical in microorganisms and its environmental implications: A review

Z He, Q Li, Y Xu, D Zhang, X Pan - Environmental Pollution, 2023 - Elsevier
Extracellular superoxide radical (O 2•−) is ubiquitous in microbial environments and has
significant implications for pollutant transformation. Microbial extracellular O 2•− can be …

Enediyne natural product biosynthesis unified by a diiodotetrayne intermediate

C Gui, E Kalkreuter, L Lauterbach, D Yang… - Nature Chemical …, 2024 - nature.com
Enediyne natural products are renowned for their potent cytotoxicities but the biosynthesis of
their defining 1, 5-diyne-3-ene core moiety remains largely enigmatic. Since the discovery of …

[HTML][HTML] Conformational coupling of redox-driven Na+-translocation in Vibrio cholerae NADH:quinone oxidoreductase

JL Hau, S Kaltwasser, V Muras, MS Casutt… - Nature Structural & …, 2023 - nature.com
In the respiratory chain, NADH oxidation is coupled to ion translocation across the
membrane to build up an electrochemical gradient. In the human pathogen Vibrio cholerae …

Architecture of the RNF1 complex that drives biological nitrogen fixation

L Zhang, O Einsle - Nature Chemical Biology, 2024 - nature.com
Biological nitrogen fixation requires substantial metabolic energy in form of ATP as well as
low-potential electrons that must derive from central metabolism. During aerobic growth, the …

Respiratory protein interactions in Dehalobacter sp. strain 8M revealed through genomic and native proteomic analyses

JM Soder‐Walz, K Wasmund… - Environmental …, 2023 - Wiley Online Library
Dehalobacter (Firmicutes) encompass obligate organohalide‐respiring bacteria used for
bioremediation of groundwater contaminated with halogenated organics. Various aspects of …

[HTML][HTML] Matrine attenuating cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity through improved mitochondrial membrane potential and activation of …

C Erfu, L Li, Q Weiting, C Tao, M Liwei, Y Hemin… - Biomedicine & …, 2024 - Elsevier
The study aimed to demonstrate that matrine can reduce apoptosis in H9c2 cells induced by
the cardiotoxic anticancer drug doxorubicin (DOX). The researchers pretreated H9c2 cells …

[HTML][HTML] Respiratory complex I in mitochondrial membrane catalyzes oversized ubiquinones

R Ikunishi, R Otani, T Masuya, K Shinzawa-Itoh… - Journal of Biological …, 2023 - ASBMB
NADH-ubiquinone (UQ) oxidoreductase (complex I) couples electron transfer from NADH to
UQ with proton translocation in its membrane part. The UQ reduction step is key to triggering …

[HTML][HTML] Identification of complex III, NQR, and SDH as primary bioenergetic enzymes during the stationary phase of Pseudomonas aeruginosa cultured in urine-like …

Y Hu, M Yuan, A Julian, K Tuz, O Juárez - Frontiers in Microbiology, 2024 - frontiersin.org
Pseudomonas aeruginosa is a common cause of urinary tract infections by strains that are
often multidrug resistant, representing a major challenge to the world's health care system …

Identifying therapeutic antibacterial peptides against Vibrio cholerae to inhibit the function of Na(+)-translocating NADH-quinone reductase

OAS Baothman - Journal of Biomolecular Structure and Dynamics, 2023 - Taylor & Francis
Vibrio cholerae is the bacteria responsible for cholera, which is a significant threat to many
nations. Curing and treating this infection requires identification of the critical protein and …

[HTML][HTML] Functionality of the Na+-translocating NADH:quinone oxidoreductase and quinol:fumarate reductase from Prevotella bryantii inferred from homology …

JL Hau, L Schleicher, S Herdan, J Simon, J Seifert… - Archives of …, 2024 - Springer
Members of the family Prevotellaceae are Gram-negative, obligate anaerobic bacteria found
in animal and human microbiota. In Prevotella bryantii, the Na+-translocating NADH …