The roles of serotonin in neuropsychiatric disorders

M Pourhamzeh, FG Moravej, M Arabi… - Cellular and molecular …, 2022 - Springer
The serotonergic system extends throughout the central nervous system (CNS) and the
gastrointestinal (GI) tract. In the CNS, serotonin (5-HT, 5-hydroxytryptamine) modulates a …

Harmonizing the neurobiology and treatment of obsessive-compulsive disorder

WK Goodman, EA Storch… - American Journal of …, 2021 - Am Psychiatric Assoc
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling
disorder. The only established first-line treatments for OCD are exposure and response …

Psychopharmacological treatment of obsessive-compulsive disorder (OCD)

A Del Casale, S Sorice, A Padovano… - Current …, 2019 - ingentaconnect.com
Background: Obsessive-compulsive disorder (OCD) is associated with affective and
cognitive symptoms causing personal distress and reduced global functioning. These have …

Obsessive–compulsive disorder

DJ Stein, DLC Costa, C Lochner, EC Miguel… - Nature reviews Disease …, 2019 - nature.com
Obsessive–compulsive disorder (OCD) is a highly prevalent and chronic condition that is
associated with substantial global disability. OCD is the key example of the 'obsessive …

Pharmacological treatment of obsessive-compulsive disorder

C Pittenger, MH Bloch - Psychiatric Clinics, 2014 - psych.theclinics.com
Obsessive-compulsive disorder (OCD) can present a significant management challenge to
the clinical psychiatrist. OCD affects approximately 1.3% of the population in any given year …

Cognitive-behavioral therapy vs risperidone for augmenting serotonin reuptake inhibitors in obsessive-compulsive disorder: a randomized clinical trial

HB Simpson, EB Foa, MR Liebowitz, JD Huppert… - JAMA …, 2013 - jamanetwork.com
Importance Obsessive-compulsive disorder (OCD) is one of the world's most disabling
illnesses according to the World Health Organization. Serotonin reuptake inhibitors (SRIs) …

Repetitive transcranial magnetic stimulation (rTMS) for obsessive–compulsive disorder (OCD): an exploratory meta-analysis of randomized and sham-controlled trials

MT Berlim, NH Neufeld, F Van den Eynde - Journal of psychiatric research, 2013 - Elsevier
OBJECTIVE: Randomized and sham-controlled trials (RCTs) on repetitive transcranial
magnetic stimulation (rTMS) for treating obsessive–compulsive disorder (OCD) have yielded …

[HTML][HTML] Treatment-resistant OCD: Pharmacotherapies in adults

PJ Van Roessel, G Grassi, EN Aboujaoude… - Comprehensive …, 2023 - Elsevier
Serotonin reuptake inhibitor (SRI) medications are well established as first-line
pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD). However …

Treatment-refractory anxiety; definition, risk factors, and treatment challenges

P Roy-Byrne - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
A sizable proportion of psychiatric patients will seek clinical evaluation and treatment for
anxiety symptoms reportedly refractory to treatment. This apparent lack of response is either …

Neuroscientifically informed formulation and treatment planning for patients with obsessive-compulsive disorder: a review

DD Dougherty, BP Brennan, SE Stewart… - Jama …, 2018 - jamanetwork.com
Importance Obsessive-compulsive disorder (OCD) is a common and often debilitating
psychiatric illness. Recent advances in the understanding of the neuroscience of OCD have …