Cationic liposome–DNA complexes (lipoplexes) constitute a potentially viable alternative to
viral vectors for the delivery of therapeutic genes. This review will focus on various …

Reconstructive therapies to promote the regeneration of lost periodontal support have been
investigated through both preclinical and clinical studies. Advanced regenerative …

Gene therapy aims to revert diseased phenotypes by the use of both viral and nonviral gene
delivery systems. Substantial progress has been made in making gene transfer vehicles …

The pathogenesis of primary Sjögren's syndrome is complex and the factors initiating and
driving autoimmunity in this entity are largely unknown. Recent studies provide new insights …

Current knowledge about the pathogenesis of periodontal diseased obtained mainly from
the results of animal experiments, analysis of periodontal histopathology, epidemiologic …

The multi-walled carbon nanotubes (MWCNTs)-polyamidoamine (PAMAM) hybrid was
prepared by covalent linkage approach, and characterized by transmission electron …

Regional gene therapy techniques are promising methods to enhance bone formation in
large bone defects that would be difficult to treat with allograft or autograft bone stock. In this …

Study Design. A recombinant baculovirus vector expressing GFP (Ac-CMV-GFP) was tested
in rabbit intervertebral disc cells cultured in monolayer in vitro. Direct infection of …

Aims Peripheral chemoreflex sensitivity is potentiated in both clinical and experimental
chronic heart failure (CHF). NADPH oxidase-derived superoxide mediates angiotensin II …

Directing the local or systemic expression of therapeutic proteins is a potentially important
clinical application of gene transfer technology. Gene-based therapeutics theoretically offer …