Botulinum toxin management of spasmodic dysphonia (laryngeal dystonia): a 12‐year experience in more than 900 patients

A Blitzer, MF Brin, CF Stewart - The Laryngoscope, 1998 - Wiley Online Library
Objectives: This paper reviews a 12‐year experience in more than 900 patients with
spasmodic dysphonia who have been treated with botulinum toxin. Study Design: This is a …

Tyrosine hydroxylase and Parkinson's disease

J Haavik, K Toska - Molecular neurobiology, 1998 - Springer
A consistent neurochemical abnormality in Parkinson's disease (PD) is degeneration of
dopaminergic neurons in substantia nigra, leading to a reduction of striatal dopamine (DA) …

The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein

LJ Ozelius, JW Hewett, CE Page, SB Bressman… - Nature …, 1997 - nature.com
Early-onset torsion dystonia is a movement disorder, characterized by twisting muscle
contractures, that begins in childhood. Symptoms are believed to result from altered …

[图书][B] Analysis of human genetic linkage

J Ott - 1999 - books.google.com
The first and still the only book of its kind, this volume offers a concise introduction to human
genetic linkage analysis and gene mapping. Jurg Ott provides mathematical and statistical …

Idiopathic cervical dystonia: clinical characteristics

J Chan, MF Brin, S Fahn - Movement disorders: official journal …, 1991 - Wiley Online Library
We reviewed detailed clinical features of 266 patients with idiopathic cervical dystonia,
commonly called spasmodic torticollis. Mean age at onset (41 years), female‐to‐male ratio …

A systematic review on the diagnosis and treatment of primary (idiopathic) dystonia and dystonia plus syndromes: report of an EFNS/MDS‐ES Task Force

A Albanese, MP Barnes, KP Bhatia… - European journal of …, 2006 - Wiley Online Library
To review the literature on primary dystonia and dystonia plus and to provide evidence‐
based recommendations. Primary dystonia and dystonia plus are chronic and often …

Genetic analysis of idiopathic torsion dystonia in Ashkenazi Jews and their recent descent from a small founder population

N Risch, D Leon, L Ozelius, P Kramer, L Almasy… - Nature …, 1995 - nature.com
We have examined data on six closely linked microsatellite loci on chromosome 9q34 from
59 Ashkenazi Jewish families with idiopathic torsion dystonia (ITD). Our data show that the …

Primary dystonia is more responsive than secondary dystonia to pallidal interventions: outcome after pallidotomy or pallidal deep brain stimulation

HA Eltahawy, J Saint-Cyr, N Giladi, AE Lang… - …, 2004 - journals.lww.com
OBJECTIVE: The response of patients with dystonia to pallidal procedures is not well
understood. In this study, we assessed the postoperative outcome of patients with primary …

[HTML][HTML] Dystonia and Parkinson's disease: what is the relationship?

AS Shetty, KP Bhatia, AE Lang - Neurobiology of disease, 2019 - Elsevier
Dystonia and Parkinson's disease are closely linked disorders sharing many
pathophysiological overlaps. Dystonia can be seen in 30% or more of the patients suffering …

Localization of disinhibition-dementia-parkinsonism-amyotrophy complex to 17q21-22.

KC Wilhelmsen, T Lynch, E Pavlou… - American journal of …, 1994 - ncbi.nlm.nih.gov
Disinhibition-dementia-parkinsonism-amyotrophy complex (DDPAC) is defined by familial
adult-onset behavioral disturbance, followed by frontal lobe dementia, parkinsonism, and …