Gender plays a crucial role in the occurrence and development of cancer, as well as in the
metabolism of nutrients and energy. Men and women display significant differences in the …

Cancer stem cells (CSCs) control tumor occurrence and development, chemotherapy
tolerance, and cancer recurrence and metastasis due to their characteristics of high …

The RNA binding protein ADAR3 is expressed exclusively in the brain and reported to have
elevated expression in tumors of patients suffering from glioblastoma compared to adjacent …

Ovarian cancer (OCa) is the deadliest gynecologic cancer. Emerging studies suggest
ovarian cancer stem cells (OCSCs) contribute to chemotherapy resistance and tumor …

The bioavailability of flavonoids is generally low after oral administration. The metabolic
transformation of flavonoids by the gut microbiota may be one of the main reasons for this …

Gliomas constitute a diverse and complex array of tumors within the central nervous system
(CNS), characterized by a wide range of prognostic outcomes and responses to therapeutic …

Estrogen and estrogen receptors (ERα and ERβ) regulate a multitude of complicated
physiological and pathological processes. Jan-Ake Gustafsson's group discovered ERβ in …

Glioblastoma (GB) is the most aggressive and frequent tumor in the central nervous system
and, in humans, represents the worst prognosis for cancer. GB develops a very complex …

Glioblastoma (GBM) is the most prevalent and aggressive type of adult brain tumors with low
5-year overall survival rates. Epidemiologic data suggest that estrogen may decrease brain …

Background: Glioblastoma (GBM) incidence is higher in males, suggesting sex hormones
may influence GBM tumorigenesis. Patients with GBM and altered sex hormone states could …