Objectives Chromosomal microarray analysis (CMA) is utilized in prenatal diagnosis to
detect chromosomal abnormalities not visible by conventional karyotyping. A prospective …

Objective To estimate the incremental yield of detecting copy number variants (CNVs) by
genomic microarray over karyotyping in fetuses with increased nuchal translucency (NT) …

Objective The aim of this study is to understand the diagnostic utility of comparative genomic
hybridization (CGH)‐based microarrays for pregnancies with abnormal ultrasound findings …

Objective Array comparative genomic hybridization (CGH) is transforming clinical
cytogenetics with its ability to interrogate the human genome at increasingly high resolution …

ABSTRACT OBJECTIVE To establish the prevalence of submicroscopic genetic copy
number variants (CNVs) in fetuses with a structural ultrasound anomaly (restricted to one …

The ability of chromosome microarray analysis (CMA) to detect submicroscopic genetic
abnormalities has revolutionized the clinical diagnostic approach to individuals with …

Objective To evaluate the results of prenatal chromosomal microarray analysis (CMA) on>
1000 fetal samples referred for testing at our institution and to compare these data to …

In this study, we aimed to explore the utility of chromosomal microarray analysis (CMA) in
groups of pregnancies with a priori low risk for detection of submicroscopic chromosome …

Objectives To assess the frequency of karyotype abnormalities and chromosome 22q11. 2
deletion syndrome among fetuses with abnormal cardiac ultrasound findings, and to …

Background The implementation of microarray analysis in prenatal diagnostics is a topic of
discussion, as rare copy number variants with unknown/uncertain clinical consequences are …