Yeast as a model to study protein misfolding in aged cells
SE Di Gregorio, ML Duennwald - FEMS yeast research, 2018 - academic.oup.com
Yeast models of neurodegenerative diseases associated with protein misfolding and protein
aggregation have given unique insights into the underlying genetic and cellular …
aggregation have given unique insights into the underlying genetic and cellular …
Yeast models of neurodegenerative diseases
MF Tuite - Progress in molecular biology and translational …, 2019 - Elsevier
The yeast Saccharomyces cerevisiae has been used to develop a wide range of highly
tractable living models of the major human neurodegenerative diseases. Yet even though …
tractable living models of the major human neurodegenerative diseases. Yet even though …
Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the …
Hsp90 is a conserved molecular chaperone that assists in the folding and function of diverse
cellular regulators, with a profound impact on biology, disease, and evolution. As a central …
cellular regulators, with a profound impact on biology, disease, and evolution. As a central …
The proteasome governs fungal morphogenesis via functional connections with Hsp90 and cAMP-protein kinase a signaling
Protein homeostasis is critical for proliferation and viability of all organisms. For Candida
albicans, protein homeostasis also modulates the transition between yeast and filamentous …
albicans, protein homeostasis also modulates the transition between yeast and filamentous …
Expression of Huntingtin and TDP-43 derivatives in fission yeast can cause both beneficial and toxic effects
L Marte, S Boronat, R Barrios… - International Journal of …, 2022 - mdpi.com
Many neurodegenerative disorders display protein aggregation as a hallmark, Huntingtin
and TDP-43 aggregates being characteristic of Huntington disease and amyotrophic lateral …
and TDP-43 aggregates being characteristic of Huntington disease and amyotrophic lateral …
Candida albicans a comprehensive view of the proteome
L Gomez Artiguez, S de la Camara Fuentes, Z Sun… - bioRxiv, 2024 - biorxiv.org
We describe a new release of the Candida albicans PeptideAtlas proteomics spectral
resource (build 2024-03), providing a sequence coverage of 79.5% at the canonical protein …
resource (build 2024-03), providing a sequence coverage of 79.5% at the canonical protein …
[PDF][PDF] Absorbance thickness in the formation of biofilm produced by Candida albicans due to glucose, lactose, protein (soy) and iron induction
Candida albicans (C. albicans) is a major cause of Candidiasis in the oral cavity.
Carbohydrates and protein are required by the fungI to grow when it is infecting the soft …
Carbohydrates and protein are required by the fungI to grow when it is infecting the soft …
In vitro aggregating β-lactamase-polyQ chimeras do not induce toxic effects in an in vivo Caenorhabditis elegans model
R Van Assche, C Borghgraef, J Vaneyck… - Journal of negative …, 2017 - Springer
Background A series of human diseases are caused by the misfolding and aggregation of
specific proteins or peptides into amyloid fibrils; nine of these diseases, referred to as …
specific proteins or peptides into amyloid fibrils; nine of these diseases, referred to as …
[图书][B] Extrachromosomal regulators of phenotypic heterogeneity in Saccharomyces species
LA Petch - 2020 - search.proquest.com
Phenotypic heterogeneity in the yeast Saccharomyces cerevisiae has input from both
genetic and epigenetic determinants. In addition to changes in DNA sequence induced by …
genetic and epigenetic determinants. In addition to changes in DNA sequence induced by …