Background Hyponatremia (serum sodium lower than 135 mmol/L) is the most frequent
electrolyte alteration diagnosed in medical practice. It has deleterious clinical effects, being …

Hyponatremia is the most common clinical electrolyte disorder. Chronic hyponatremia has
been recently reported to be associated with falls, fracture, osteoporosis, neurocognitive …

Background Hyponatremia is frequent in older age; whether it is a key player, a surrogate
marker, or an innocent bystander in age-related diseases is still unclear. Objective: To …

This article will discuss the consequences of chronic hyponatremia. In conditions such as
cancer, heart failure, liver cirrhosis, or chronic kidney disease, the presence and magnitude …

Importance The syndrome of inappropriate antidiuresis (SIAD) can be treated with oral urea;
however, compliance is impaired by its poor palatability. Objective To investigate whether …

Purpose To determine prevalences of common geriatric syndromes in the setting of different
normal ranges of serum sodium. Methods In this cross-sectional study, 2048 older adults …

Objective: Hyponatremia and sarcopenia in advanced chronic liver disease (ACLD) are both
associated with portal hypertension (PHT) and worse prognosis. This study investigated …

Background Major depressive disorder is one of the most common psychiatric disorders,
which is associated with a high disease burden. Current treatments using antidepressants …

Context Thiazide-induced hyponatremia is one of the most common forms of hyponatremia,
but its pathogenesis is incompletely understood. Recent clinical data suggest links with …

Background Acute neurologic effects of severe hyponatremia are well-known. However, the
long-term association of hyponatremia with cognitive impairment is unclear. Methods In this …