The use of ozone (O 3) gas as a therapy in alternative medicine has attracted skepticism due
to its unstable molecular structure. However, copious volumes of research have provided …

Background People with diabetes are at high risk for developing foot ulcers, which often
become infected. These wounds, especially when infected, cause substantial morbidity …

Aims Principles of wound management, including debridement, wound bed preparation, and
newer technologies involving alternation of wound physiology to facilitate healing, are of …

Background It is critical that interventions used to enhance the healing of chronic foot ulcers
in diabetes are backed by high‐quality evidence and cost‐effectiveness. In previous years …

The outcome of management of diabetic foot ulcers remains a challenge, and there remains
continuing uncertainty concerning optimal approaches to management. It is for these …

Background: Nonhealing ulcers affect patient quality of life and impose a substantial
financial burden on the health care system. Purpose: To systematically evaluate benefits …

Chronic wounds present a significant burden to the health care system and the patient.
Ozone therapy has been proposed as a treatment for chronic wounds, potentially acting by …

Management of diabetic foot ulcers (DFUs) is a great challenge for clinicians. Although the
oxygen‐ozone treatment improves the diabetic outcome, there are few clinical trials to verify …

This study aims at evaluating the efficacy and safety of ozone therapy for chronic wounds.
The Cochrane Library, PubMed, Ovid Embase, Web of Science, and Chinese Biomedical …

The management of diabetic foot ulcers (DFU) remains a challenge, and there is continuing
uncertainty concerning optimal approaches to wound healing. The International Working …