The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of …

RIG Holt, JH DeVries, A Hess-Fischl, IB Hirsch… - Diabetes …, 2021 - Am Diabetes Assoc
The American Diabetes Association (ADA) and the European Association for the Study of
Diabetes (EASD) convened a writing group to develop a consensus statement on the …

14. Children and Adolescents: Standards of Care in Diabetes—2023

NA ElSayed, G Aleppo, VR Aroda, RR Bannuru… - Diabetes …, 2023 - Am Diabetes Assoc
The American Diabetes Association (ADA)“Standards of Care in Diabetes” includes the
ADA's current clinical practice recommendations and is intended to provide the components …

Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps

Nature medicine, 2021 - nature.com
Polygenic risk scores (PRSs) aggregate the many small effects of alleles across the human
genome to estimate the risk of a disease or disease-related trait for an individual. The …

Type 1 diabetes

LA DiMeglio, C Evans-Molina, RA Oram - The Lancet, 2018 - thelancet.com
Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and
resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past …

Precision medicine in diabetes: a consensus report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

WK Chung, K Erion, JC Florez, AT Hattersley… - Diabetes …, 2020 - Am Diabetes Assoc
The convergence of advances in medical science, human biology, data science, and
technology has enabled the generation of new insights into the phenotype known as …

Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of SARS-CoV-2: a Mendelian randomization analysis …

S Rao, A Lau, HC So - Diabetes care, 2020 - Am Diabetes Assoc
OBJECTIVE COVID-19 has become a major public health problem. There is good evidence
that ACE2 is a receptor for SARS-CoV-2, and high expression of ACE2 may increase …

Adult-onset type 1 diabetes: current understanding and challenges

RD Leslie, C Evans-Molina, J Freund-Brown… - Diabetes …, 2021 - Am Diabetes Assoc
Recent epidemiological data have shown that more than half of all new cases of type 1
diabetes occur in adults. Key genetic, immune, and metabolic differences exist between …

Prevalence of diagnosed type 1 and type 2 diabetes among US adults in 2016 and 2017: population based study

G Xu, B Liu, Y Sun, Y Du, LG Snetselaar, FB Hu, W Bao - Bmj, 2018 - bmj.com
Objective To estimate the prevalence of diagnosed total diabetes, type 1 diabetes, and type
2 diabetes in the US general population and the proportions of each among US adults with a …

[HTML][HTML] Life expectancy associated with different ages at diagnosis of type 2 diabetes in high-income countries: 23 million person-years of observation

S Kaptoge, SRK Seshasai, L Sun, M Walker… - The Lancet Diabetes & …, 2023 - thelancet.com
Background The prevalence of type 2 diabetes is increasing rapidly, particularly among
younger age groups. Estimates suggest that people with diabetes die, on average, 6 years …

Type 1 diabetes

T Quattrin, LD Mastrandrea, LSK Walker - The Lancet, 2023 - thelancet.com
Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic β
cells. Individuals with type 1 diabetes are reliant on insulin for survival. Despite enhanced …