The paradoxical pro-tumorigenic function of plasminogen activator inhibitor 1 (PAI-1, aka
Serpin E1) in cancer progression and metastasis has been the subject of an abundant …

Background. Endometrial cancer (EC) is one of the most common gynecologic malignancy,
mostly in postmenopausal women. The gold standard treatment for EC is surgery, but in the …

Abstract [Despite as a major inhibitor of urokinase (uPA), paradoxically,] Plasminogen
activator inhibitor-1 (PAI-1) has been validated to be highly expressed in various types of …

The link between obesity and multiple disease comorbidities is well established. In 2003,
Calle and colleagues presented the relationship between obesity and several cancer types …

Background The gold standard treatment for early-stage endometrial cancer (EC) is
hysterectomy with bilateral salpingo-oophorectomy (BSO) with lymphadenectomy. In …

Long non-coding RNAs play an important role in tumor growth, angiogenesis, and
metastasis in several types of cancer. However, the clinical significance of using lncRNAs as …

Abstract Background Antiphospholipid Syndrome (APS) is an autoimmune multifactorial
disorder. Genetics is believed to play a contributory role in the pathogenesis of APS …

Background Endometrial cancer is the fourth most frequent gynecological cancer and the
most frequent type of uterine cancer. There is an increase in the incidence and mortality of …

Gynecological medicine involves the diagnoses and treatment of illnesses and issues
involving female reproductive organs. This review is focused on female cancers of their …

Background: The plasminogen activator inhibitor-1 (PAI-1) was found in many types of tumor
cells, which involved in tumorigenesis. Some studies investigated the associations between …