Bacterial infections associated with biomedical devices and implants have posed a great
challenge to global healthcare systems. These infections are mainly caused by bacterial …

The global surge of antimicrobial resistance (AMR) is a major concern for public health and
proving to be a key challenge in modern disease treatment, requiring action plans at all …

Bacterial infection raises serious concerns in tissue repair settings involved with implantable
biomaterials, devastating the regenerative process and even life-threatening. When hard …

The therapeutic challenges of orthopedic device-related infections and emerging
antimicrobial resistance have attracted attention to drug delivery technologies. This study …

To prevent infections local delivery of antibiotics is a useful tool. Especially in bone fractures,
vancomycin impregnated bone cements are often used allowing high concentrations of …

Introduction Infection after total knee arthroplasty (TKA) impacts the patient, surgeon, and
healthcare system significantly. Surgeons routinely use antibiotic-loaded bone cement …

Antibiotic bone cement (ABC) is an effective tool for the prophylaxis and treatment of
osteomyelitis due to the controlled, sustained release of local antibiotics. ABC has been …

Infection is a leading cause of total joint arthroplasty failure. Current preventative measures
incorporate antibiotics into the poly (methyl methacrylate)(PMMA) bone cement that anchors …

Aims Intra-articular administration of antibiotics during primary total knee arthroplasty (TKA)
may represent a safe, cost-effective strategy to reduce the risk of acute periprosthetic joint …

As medicine advances and physicians are able to provide patients with innovative solutions,
including placement of temporary or permanent medical devices that drastically improve …