Bioinformatics and machine learning methodologies to identify the effects of central nervous system disorders on glioblastoma progression

MH Rahman, HK Rana, S Peng, X Hu… - Briefings in …, 2021 - academic.oup.com
Glioblastoma (GBM) is a common malignant brain tumor which often presents as a
comorbidity with central nervous system (CNS) disorders. Both CNS disorders and GBM …

[HTML][HTML] Polygenic risk score for cardiovascular diseases in artificial intelligence paradigm: a review

NN Khanna, M Singh, M Maindarkar… - Journal of Korean …, 2023 - synapse.koreamed.org
Cardiovascular disease (CVD) related mortality and morbidity heavily strain society. The
relationship between external risk factors and our genetics have not been well established. It …

Machine learning models for classification and identification of significant attributes to detect type 2 diabetes

KC Howlader, MS Satu, MA Awal, MR Islam… - … information science and …, 2022 - Springer
Abstract Type 2 Diabetes (T2D) is a chronic disease characterized by abnormally high blood
glucose levels due to insulin resistance and reduced pancreatic insulin production. The …

[HTML][HTML] Systems Biology and Bioinformatics approach to Identify blood based signatures molecules and drug targets of patient with COVID-19

MI Hasan, MH Rahman, MB Islam, MZ Islam… - Informatics in Medicine …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection results in the
development of a highly contagious respiratory ailment known as new coronavirus disease …

[HTML][HTML] In silico molecular docking and ADME/T analysis of Quercetin compound with its evaluation of broad-spectrum therapeutic potential against particular …

MM Hasan, Z Khan, MS Chowdhury, MA Khan… - Informatics in Medicine …, 2022 - Elsevier
Progression in computational research has made it possible for the in silico methods to offer
epochal benefits to both regulatory needs and the pharmaceutical industry to assess the …

Bioinformatics and system biology approaches to identify pathophysiological impact of COVID-19 to the progression and severity of neurological diseases

MH Rahman, HK Rana, S Peng, MG Kibria… - Computers in biology …, 2021 - Elsevier
Abstract The Coronavirus Disease 2019 (COVID-19) still tends to propagate and increase
the occurrence of COVID-19 across the globe. The clinical and epidemiological analyses …

[HTML][HTML] An integrated in-silico Pharmaco-BioInformatics approaches to identify synergistic effects of COVID-19 to HIV patients

MA Hossain, MH Rahman, H Sultana, A Ahsan… - Computers in Biology …, 2023 - Elsevier
Background With high inflammatory states from both COVID-19 and HIV conditions further
result in complications. The ongoing confrontation between these two viral infections can be …

DNA methylation and expression profiles of placenta and umbilical cord blood reveal the characteristics of gestational diabetes mellitus patients and offspring

S Lu, J Wang, N Kakongoma, W Hua, J Xu, Y Wang… - Clinical …, 2022 - Springer
Background Gestational diabetes mellitus (GDM) is a common pregnancy-specific disease
and is growing at an alarming rate worldwide, which can negatively affect the health of …

Integrated bioinformatics analysis reveals marker genes and immune infiltration for pulmonary arterial hypertension

S Tang, Y Liu, B Liu - Scientific reports, 2022 - nature.com
Pulmonary arterial hypertension (PAH) is a chronic cardiopulmonary syndrome with high
pulmonary vascular load and eventually causing RV heart failure even death. However, the …

Bioinformatics and system biological approaches for the identification of genetic risk factors in the progression of cardiovascular disease

JD Barua, SBS Omit, HK Rana… - Cardiovascular …, 2022 - Wiley Online Library
Background. Cardiovascular disease (CVD) is the combination of coronary heart disease,
myocardial infarction, rheumatic heart disease, and peripheral vascular disease of the heart …