Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

Actin dynamics in cell motility, division, and phagocytosis is regulated by complex factors
with multiple feedback loops, often leading to emergent dynamic patterns in the form of …

Much of current understanding of cell motility arose from studying steady treadmilling of actin
arrays. Recently, there have been a growing number of observations of a more complex …

Computational modelling of cell motility on substrates is a formidable challenge; regulatory
pathways are intertwined and forces that influence cell motion are not fully quantified …

Despite the prevalence of superresolution (SR) microscopy, quantitative live-cell SR
imaging that maintains the completeness of delicate structures and the linearity of …

Actin filaments and associated proteins undergo wave-like movement in various cell types.
Recent studies with cutting-edge analyses, including live-cell imaging, biophysical …

The actin cytoskeleton in motile cells has many of the hallmarks of an excitable medium,
including the presence of propagating waves. This excitable behavior can account for the …

One of the most fundamental features of biological systems is probably their ability to self-
organize in space and time on different scales. Despite many elaborate theoretical models …

Dynamic processes in living cells are highly organized in space and time. Unraveling the
underlying molecular mechanisms of spatiotemporal pattern formation remains one of the …

Numerous models explain how cells sense and migrate towards shallow chemoattractant
gradients. Studies show that an excitable signal transduction network acts as a pacemaker …