[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism

PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …

Chasing bacterial chassis for metabolic engineering: a perspective review from classical to non‐traditional microorganisms

P Calero, PI Nikel - Microbial Biotechnology, 2019 - Wiley Online Library
The last few years have witnessed an unprecedented increase in the number of novel
bacterial species that hold potential to be used for metabolic engineering. Historically …

Functional genetics of human gut commensal Bacteroides thetaiotaomicron reveals metabolic requirements for growth across environments

H Liu, AL Shiver, MN Price, HK Carlson, VV Trotter… - Cell reports, 2021 - cell.com
Harnessing the microbiota for beneficial outcomes is limited by our poor understanding of
the constituent bacteria, as the functions of most of their genes are unknown. Here, we …

Genome-Wide Identification of Tomato Xylem Sap Fitness Factors for Three Plant-Pathogenic Ralstonia Species

SJ Georgoulis, KE Shalvarjian, TC Helmann… - Msystems, 2021 - Am Soc Microbiol
Plant-pathogenic Ralstonia spp. colonize plant xylem and cause wilt diseases on a broad
range of host plants. To identify genes that promote growth of diverse Ralstonia strains in …

Molecular and ecological perspectives of nitrous oxide producing microbial communities in agro-ecosystems

A Kumar, K Medhi, RK Fagodiya… - … Science and Bio …, 2020 - Springer
Nitrous oxide (N 2 O) is a potent greenhouse gas. Agricultural soils are the major source of
N 2 O contributing more than 70% of the global N 2 O emissions. In soil, N 2 O is mainly …

Optimized expression and enhanced production of alkaline protease by genetically modified Bacillus licheniformis 2709

C Zhou, H Zhou, D Li, H Zhang, H Wang, F Lu - Microbial cell factories, 2020 - Springer
Background Bacillus licheniformis 2709 is extensively applied as a host for the high-level
production of heterologous proteins, but Bacillus cells often possess unfavorable wild-type …

A framework for the systematic selection of biosensor chassis for environmental synthetic biology

S Sridhar, CM Ajo-Franklin, CA Masiello - ACS Synthetic Biology, 2022 - ACS Publications
Microbial biosensors sense and report exposures to stimuli, thereby facilitating our
understanding of environmental processes. Successful design and deployment of …

Pathogenic Rickettsia spp. as emerging models for bacterial biology

B Sit, RL Lamason - Journal of Bacteriology, 2024 - Am Soc Microbiol
Our understanding of free-living bacterial models like Escherichia coli far outpaces that of
obligate intracellular bacteria, which cannot be cultured axenically. All obligate intracellular …

In vivo, in vitro and in silico: an open space for the development of microbe‐based applications of synthetic biology

A Danchin - Microbial Biotechnology, 2022 - Wiley Online Library
Living systems are studied using three complementary approaches: living cells, cell‐free
systems and computer‐mediated modelling. Progresses in understanding, allowing …

Stringent response in mycobacteria: from biology to therapeutic potential

KR Gupta, G Arora, A Mattoo, A Sajid - Pathogens, 2021 - mdpi.com
Mycobacterium tuberculosis is a human pathogen that can thrive inside the host immune
cells for several years and cause tuberculosis. This is due to the propensity of M …