Epigenetics in hepatocellular carcinoma

GP Nagaraju, B Dariya, P Kasa, S Peela… - Seminars in cancer …, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and
has a high fatality rate. Genetic and epigenetic aberrations are commonly observed in HCC …

Epigenetic associations between lncRNA/circRNA and miRNA in hepatocellular carcinoma

TS Han, K Hur, HS Cho, HS Ban - Cancers, 2020 - mdpi.com
Simple Summary Non-coding RNAs such as microRNAs, long non-coding RNAs, and
circular RNAs contribute to the development and progression of hepatocellular carcinoma …

HDAC inhibitors as epigenetic regulators of the immune system: impacts on cancer therapy and inflammatory diseases

EE Hull, MKR Montgomery… - BioMed research …, 2016 - Wiley Online Library
Histone deacetylase (HDAC) inhibitors are powerful epigenetic regulators that have
enormous therapeutic potential and have pleiotropic effects at the cellular and systemic …

Epigenetics and microRNAs in cancer

A Ramassone, S Pagotto, A Veronese… - International journal of …, 2018 - mdpi.com
The ability to reprogram the transcriptional circuitry by remodeling the three-dimensional
structure of the genome is exploited by cancer cells to promote tumorigenesis. This …

Potential value of miR-221/222 as diagnostic, prognostic, and therapeutic biomarkers for diseases

J Song, Y Ouyang, J Che, X Li, Y Zhao, K Yang… - Frontiers in …, 2017 - frontiersin.org
microRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by base
pairing with their target messenger RNAs. Dysregulation of miRNAs is involved in the …

Exosomes from human urine‐derived stem cells enhanced neurogenesis via miR‐26a/HDAC6 axis after ischaemic stroke

X Ling, G Zhang, Y Xia, Q Zhu, J Zhang… - Journal of cellular …, 2020 - Wiley Online Library
Endogenous neurogenesis holds promise for brain repair and long‐term functional recovery
after ischaemic stroke. However, the effects of exosomes from human urine‐derived stem …

Immunomodulatory properties of human breast milk: microRNA contents and potential epigenetic effects

MMM Hatmal, MAI Al-Hatamleh, AN Olaimat, W Alshaer… - Biomedicines, 2022 - mdpi.com
Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …

Ultrasensitive, colorimetric detection of microRNAs based on isothermal exponential amplification reaction-assisted gold nanoparticle amplification

RD Li, BC Yin, BC Ye - Biosensors and Bioelectronics, 2016 - Elsevier
MicroRNAs (miRNAs) play important roles in a wide range of biological processes, and their
aberrant expressions are linked to a large number of human diseases and disorders. In this …

The epigenetic modulation of cancer and immune pathways in hepatitis B virus-associated hepatocellular carcinoma: the influence of HBx and miRNA dysregulation

K Sartorius, P An, C Winkler, A Chuturgoon… - Frontiers in …, 2021 - frontiersin.org
Hepatitis B virus (HBV)-associated hepatocellular carcinoma (HBV-HCC) pathogenesis is
fueled by persistent HBV infection that stealthily maintains a delicate balance between viral …

Dysregulated miRNA in progression of hepatocellular carcinoma: A systematic review

Y Mizuguchi, T Takizawa, H Yoshida… - Hepatology …, 2016 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the fifth most frequent cancer and the third cause of
cancer‐related mortality worldwide. The primary risk factor for HCC is liver cirrhosis …