[HTML][HTML] Understanding mitochondrial complex I assembly in health and disease

M Mimaki, X Wang, M McKenzie, DR Thorburn… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Complex I (NADH: ubiquinone oxidoreductase) is the largest multimeric enzyme complex of
the mitochondrial respiratory chain, which is responsible for electron transport and the …

The oxidative phosphorylation system in mammalian mitochondria

S Papa, PL Martino, G Capitanio, A Gaballo… - Advances in …, 2012 - Springer
The chapter provides a review of the state of art of the oxidative phosphorylation system in
mammalian mitochondria. The sections of the paper deal with:(i) the respiratory chain as a …

[HTML][HTML] The genome of Naegleria gruberi illuminates early eukaryotic versatility

LK Fritz-Laylin, SE Prochnik, ML Ginger, JB Dacks… - Cell, 2010 - cell.com
Genome sequences of diverse free-living protists are essential for understanding eukaryotic
evolution and molecular and cell biology. The free-living amoeboflagellate Naegleria …

Mammalian mitochondrial complex I: biogenesis, regulation, and reactive oxygen species generation

WJH Koopman, LGJ Nijtmans… - Antioxidants & redox …, 2010 - liebertpub.com
Virtually every mammalian cell contains mitochondria. These double-membrane organelles
continuously change shape and position and contain the complete metabolic machinery for …

Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease

F Distelmaier, WJH Koopman, LP Van Den Heuvel… - Brain, 2009 - academic.oup.com
Mitochondria are essential for cellular bioenergetics by way of energy production in the form
of ATP through the process of oxidative phosphorylation. This crucial task is executed by five …

Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject

G Lenaz, ML Genova - Antioxidants & redox signaling, 2010 - liebertpub.com
The enzymatic complexes of the mitochondrial respiratory chain have been extensively
investigated in their structural and functional properties. A clear distinction is possible today …

Internal Architecture of Mitochondrial Complex I from Arabidopsis thaliana

J Klodmann, S Sunderhaus, M Nimtz, L Jänsch… - The Plant …, 2010 - academic.oup.com
The NADH dehydrogenase complex (complex I) of the respiratory chain has unique features
in plants. It is the main entrance site for electrons into the respiratory electron transfer chain …

Assembly factors of human mitochondrial respiratory chain complexes: physiology and pathophysiology

D Ghezzi, M Zeviani - … : Nuclear-Encoded Genes, Enzyme Regulation, and …, 2012 - Springer
Mitochondrial disorders are clinical syndromes associated with abnormalities of the
oxidative phosphorylation (OXPHOS) system, the main responsible for the production of …

Massive gene loss in mistletoe (Viscum, Viscaceae) mitochondria

G Petersen, A Cuenca, IM Møller, O Seberg - Scientific reports, 2015 - nature.com
Parasitism is a successful survival strategy across all kingdoms and has evolved repeatedly
in angiosperms. Parasitic plants obtain nutrients from other plants and some are agricultural …

The life of plant mitochondrial complex I

HP Braun, S Binder, A Brennicke, H Eubel, AR Fernie… - Mitochondrion, 2014 - Elsevier
The mitochondrial NADH dehydrogenase complex (complex I) of the respiratory chain has
several remarkable features in plants:(i) particularly many of its subunits are encoded by the …