Cognitive disorders in people living with HIV

A Winston, S Spudich - The Lancet HIV, 2020 - thelancet.com
High rates of cognitive disorders in antiretroviral-treated people living with HIV have been
described worldwide. The exact prevalence of such cognitive disorders is determined by the …

Efavirenz and the CNS: what we already know and questions that need to be answered

N Apostolova, HA Funes, A Blas-Garcia… - Journal of …, 2015 - academic.oup.com
The NNRTI efavirenz has long been one of the most frequently employed antiretroviral drugs
in the multidrug regimens used to treat HIV infection, in accordance with its well …

Independent effects of HIV, aging, and HAART on brain volumetric measures

BM Ances, M Ortega, F Vaida, J Heaps… - JAIDS Journal of …, 2012 - journals.lww.com
Background: Neurocognitive impairment remains prevalent in HIV-infected (HIV+)
individuals despite highly active antiretroviral therapy (HAART). We assessed the impact of …

Assessment, diagnosis, and treatment of HIV-associated neurocognitive disorder: a consensus report of the mind exchange program

Mind Exchange Working Group… - Clinical Infectious …, 2013 - academic.oup.com
Many practical clinical questions regarding the management of human immunodeficiency
virus (HIV)–associated neurocognitive disorder (HAND) remain unanswered. We sought to …

CNS neurotoxicity of antiretrovirals

T Lanman, S Letendre, Q Ma, A Bang… - Journal of Neuroimmune …, 2021 - Springer
The development of novel antiretroviral treatments has led to a significant turning point in the
fight against HIV. Although therapy leads to virologic suppression and prolonged life …

Management of human immunodeficiency virus infection in advanced age

M Greene, AC Justice, HW Lampiris, V Valcour - Jama, 2013 - jamanetwork.com
Importance Human immunodeficiency virus (HIV)− positive patients treated with
antiretroviral therapy now have increased life expectancy and develop chronic illnesses that …

Neurological and psychiatric adverse effects of antiretroviral drugs

MS Abers, WX Shandera, JS Kass - CNS drugs, 2014 - Springer
Antiretroviral drugs are associated with a variety of adverse effects on the central and
peripheral nervous systems. The frequency and severity of neuropsychiatric adverse events …

Long-term efavirenz use is associated with worse neurocognitive functioning in HIV-infected patients

Q Ma, F Vaida, J Wong, CA Sanders, Y Kao… - Journal of …, 2016 - Springer
Neurocognitive (NC) complications continue to afflict a substantial proportion of HIV-infected
people taking effective antiretroviral therapy (ART). One contributing mechanism for this is …

[PDF][PDF] BHIVA guidelines on antiretroviral treatment for adults living with HIV-1 2022

L Waters, A Winston, I Reeves, M Boffito… - HIV …, 2022 - discovery.ucl.ac.uk
The overall purpose of these guidelines is to provide guidance on best clinical practice for
antiretroviral therapy (ART) and management of adults living with human immunodeficiency …

Could antiretroviral neurotoxicity play a role in the pathogenesis of cognitive impairment in treated HIV disease?

J Underwood, KR Robertson, A Winston - Aids, 2015 - journals.lww.com
Whilst effective antiretroviral therapy is protective against the more severe forms of HIV-
associated brain disease, there remains a large burden of clinically symptomatic cognitive …