The unfolded protein response (UPR) plays a central role in regulating endoplasmic
reticulum (ER) and global cellular physiology in response to pathologic ER stress. The UPR …

Simple Summary This review discusses current techniques used to study post-translational
protein modifications (PTMs) and their contribution to blood cancer research. Blood cancer …

ERBB receptor tyrosine kinases are involved in development and diseases like cancer,
cardiovascular, neurodevelopmental, and mental disorders. Although existing drugs target …

Simple Summary The purpose of this study was to analyze differential cell signaling in
response to denosumab treatment to identify and subsequently inhibit molecular targets in …

Simple Summary Children with metastatic or relapsed solid tumors remain in desperate
need of better treatment since conventional chemotherapy is often ineffective and can cause …

A lot of hope for high‐risk cancers is being pinned on immunotherapy but the evidence in
children is lacking due to the rarity and limited efficacy of single‐agent approaches. Here …

Objective MG-63 cells that have osteoblastic and adipogenic differentiation potential were
evaluated for internalization, and adipogenic differentiation in the presence and absence of …

Background. Our earlier works showed the quick vascularization of mouse skin grafted
Bombyx mori 3D silk fibroin nonwoven scaffolds (3D-SFnws) and the release of exosomes …

Tyrosine kinase inhibitors (TKIs) are frequently used in combined therapy to enhance
treatment efficacy and overcome drug resistance. The present study analyzed the effects of …

Despite constant advances in the field of pediatric oncology, the survival rate of high-risk
neuroblastoma patients remains poor. The molecular and genetic features of …