The SARS‐CoV‐2 main protease (Mpro): Structure, function, and emerging therapies for COVID‐19

Q Hu, Y Xiong, GH Zhu, YN Zhang, YW Zhang… - MedComm, 2022 - Wiley Online Library
The main proteases (Mpro), also termed 3‐chymotrypsin‐like proteases (3CLpro), are a
class of highly conserved cysteine hydrolases in β‐coronaviruses. Increasing evidence has …

Naringenin as a possible candidate against SARS-CoV-2 infection and in the pathogenesis of COVID-19

PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Naringenin, widely distributed in fruits and vegetables, is endowed with antiviral and other
health beneficial activities, such as immune-stimulating and anti-inflammatory actions that …

[HTML][HTML] A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle

S Kumar, P Paul, P Yadav, R Kaul, SS Maitra… - Computers in biology …, 2022 - Elsevier
The advent and persistence of the Severe Acute Respiratory Syndrome Coronavirus–2
(SARS-CoV-2)-induced Coronavirus Disease (COVID-19) pandemic since December 2019 …

Commercially available flavonols are better SARS-CoV-2 inhibitors than isoflavone and flavones

OA Chaves, N Fintelman-Rodrigues, X Wang… - Viruses, 2022 - mdpi.com
Despite the fast development of vaccines, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is still circulating and generating variants of concern (VoC) that escape the …

Molecular interactions of tannic acid with proteins associated with SARS-CoV-2 infectivity

M Haddad, R Gaudreault, G Sasseville… - International journal of …, 2022 - mdpi.com
The overall impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on
our society is unprecedented. The identification of small natural ligands that could prevent …

The role of micronutrients to support immunity for COVID-19 prevention

MH Ahmed, A Hassan, J Molnár - Revista Brasileira de Farmacognosia, 2021 - Springer
Abstract The World Health Organization declared the novel coronavirus, named as SARS-
CoV-2, as a global pandemic in early 2020 after the disease spread to more than 180 …

Bioactivity and Pharmacological Potential of Date Palm (Phoenix dactylifera L.) Against Pandemic COVID-19: a Comprehensive Review

MR Ahmad Mohd Zain, Z Abdul Kari… - Applied biochemistry …, 2022 - Springer
A novel coronavirus disease (COVID-19) or severe acute respiratory syndrome-related
coronavirus 2 (SARS-CoV-2), transmitted from person to person, has quickly emerged as the …

Phytochemical Profiling and Antiviral Activity of Green Sustainable Nanoparticles Derived from Maesa indica (Roxb.) Sweet against Human Coronavirus 229E

FAM Abdelgawad, SS El-Hawary, EM Abd El-Kader… - Plants, 2023 - mdpi.com
Plant secondary metabolites are key components for new, safe and effective drugs.
Ethanolic extract of Maesa indica Roxb. Sweet (ME) aerial parts were used for biosynthesis …

Different compounds against Angiotensin-Converting Enzyme 2 (ACE2) receptor potentially containing the infectivity of SARS-CoV-2: an in silico study

B Shahbazi, L Mafakher, L Teimoori-Toolabi - Journal of molecular …, 2022 - Springer
Novel SARS coronavirus or SARS-CoV-2 is a novel coronavirus that was identified and
spread from Wuhan in 2019. On January 30th, the World Health Organization declared the …

Advances in the prophylaxis of respiratory infections by the nasal and the oromucosal route: relevance to the fight with the SARS-CoV-2 pandemic

N Ivanova, Y Sotirova, G Gavrailov, K Nikolova… - Pharmaceutics, 2022 - mdpi.com
In this time of COVID-19 pandemic, the strategies for prevention of the infection are a
primary concern. Looking more globally on the subject and acknowledging the high degree …