Fluorescence lifetime imaging ophthalmoscopy, FLIO, has gained large interest in the
scientific community in the recent years. It is a noninvasive imaging modality that has been …

Autofluorescence-based imaging techniques have become very important in the
ophthalmological field. Being noninvasive and very sensitive, they are broadly used in …

Presence of reactive oxygen species (ROS) in excess of normal physiological level results in
oxidative stress. This can lead to a range of pathological conditions including inflammation …

Purpose.: Fundus autofluorescence (FAF) cannot only be characterized by the intensity or
the emission spectrum, but also by its lifetime. As the lifetime of a fluorescent molecule is …

Purpose To determine alterations in the retina of patients with Alzheimer's disease (AD) by
the newly developed technique of fluorescence lifetime imaging ophthalmoscopy (FLIO) in a …

The time-resolved autofluorescence of the eye is used for the detection of metabolic
alteration in diabetic patients who have no signs of diabetic retinopathy. One eye from 37 …

Methods: A total of 150 eyes of 110 patients (mean age: 73.2±10.7 years) with nonexudative
AMD, as well as a healthy group of 57 eyes in 38 subjects (mean age: 66.5±8.7 years), were …

Purpose: To investigate fluorescence lifetime characteristics in patients with geographic
atrophy (GA) in eyes with age-related macular degeneration and to correlate the …

Purpose: To characterize the macular region and to investigate the influence of the macular
pigment (MP) on fundus autofluorescence (FAF) lifetimes in vivo. Methods: Forty-eight …

Purpose: The purpose of this study was to characterize fundus autofluorescence lifetimes of
retinal drusen in patients with AMD. Methods: Patients with AMD and retinal drusen and …