[HTML][HTML] Dpp/BMP signaling in flies: from molecules to biology

F Hamaratoglu, M Affolter, G Pyrowolakis - Seminars in cell & …, 2014 - Elsevier
Decapentaplegic (Dpp), the fly homolog of the secreted mammalian BMP2/4 signaling
molecules, is involved in almost all aspects of fly development. Dpp has critical functions at …

[HTML][HTML] Nuclear interpretation of Dpp signaling in Drosophila

M Affolter, T Marty, MA Vigano, A Jaźwińska - The EMBO journal, 2001 - embopress.org
Abstract Signaling by Decapentaplegic (Dpp), a member of the TGFβ superfamily of
signaling molecules similar to vertebrate BMP2 and BMP4, has been implicated in many …

Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary

X Song, MD Wong, E Kawase, R Xi, BC Ding… - 2004 - journals.biologists.com
The Drosophila ovary is an attractive system to study how niches control stem cell self-
renewal and differentiation. The niche for germline stem cells (GSCs) provides a Dpp/Bmp …

TGF‐β‐activated Smad3 represses MEF2‐dependent transcription in myogenic differentiation

D Liu, JS Kang, R Derynck - The EMBO journal, 2004 - embopress.org
Transforming growth factor β (TGF‐β) inhibits myogenesis and associated gene expression.
We previously reported that the TGF‐β signaling effector Smad3 mediates this inhibition, by …

A conserved activation element in BMP signaling during Drosophila development

A Weiss, E Charbonnier, E Ellertsdóttir… - Nature structural & …, 2010 - nature.com
The transforming growth factor β (TGF-β) family member Decapentaplegic (Dpp) is a key
regulator of patterning and growth in Drosophila development. Previous studies have …

Regulation of BMP and Activin Signaling in Drosophila

L Parker, DG Stathakis, K Arora - … Cytokines and the Phylogeny of Immunity …, 2004 - Springer
Cytokines of the TGF-β superfamily act through an evolutionarily conserved signaling
pathway to elicit a diverse range of biological responses in vertebrates as well as …

Dpp-responsive silencers are bound by a trimeric Mad-Medea complex

S Gao, J Steffen, A Laughon - Journal of Biological Chemistry, 2005 - ASBMB
Transcriptional regulation by transforming growth factor-β signaling is mediated by the Smad
family of transcription factors. It is generally accepted that Smads must interact with other …

[HTML][HTML] Transcriptional repressor and activator activities of SMA-9 contribute differentially to BMP-related signaling outputs

J Liang, L Yu, J Yin, C Savage-Dunn - Developmental biology, 2007 - Elsevier
In the nematode Caenorhabditis elegans, the BMP-related growth factor DBL-1 regulates
body size and male tail morphogenesis via a conserved receptor/Smad signaling pathway …

ZAS: C2H2 zinc finger proteins involved in growth and development

LC Wu - Gene expression, 2018 - pmc.ncbi.nlm.nih.gov
A ZAS gene encodes a large protein with two separate C2H2 zinc finger pairs that
independently bind to specific DNA sequences, including the κB motif. Three paralogous …

The Caenorhabditis elegans schnurri homolog sma-9mediates stage- and cell type-specific responses to DBL-1 BMP-related signaling

J Liang, R Lints, ML Foehr, R Tokarz, L Yu… - 2003 - journals.biologists.com
In Caenorhabditis elegans, the DBL-1 pathway, a BMP/TGFβ-related signaling cascade,
regulates body size and male tail development. We have cloned a new gene, sma-9, that …