Over the past decades, lipid‐based nanoparticle drug delivery systems (DDS) have caught
the attention of researchers worldwide, encouraging the field to rapidly develop improved …

In this modern era, with the help of various advanced technologies, medical science has
overcome most of the health-related issues successfully. Though, some diseases still remain …

Barriers are the hallmark of a healthy physiology, blood-brain barrier (BBB) being a tough
nut to crack for most of the antigens and chemical substances. The presence of tight …

Brain drug delivery may be restricted by the blood-brain barrier (BBB), and enhancement by
liposome-based drug delivery strategies has been investigated. As access to the human …

Central nervous system (CNS) diseases are among the most difficult to treat, mainly
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …

Aim To develop the topical gel containing transferosomal lidocaine as alternative to painful
local anesthetic injection. Materials and methods The transfersomes were prepared by film …

The biggest obstacle to the treatment of diseases that affect the central nervous system
(CNS) is the passage of drugs across the blood-brain barrier (BBB), a physical barrier that …

Background: Parkinson's disease (PD) is the second most common age-related
neurodegenerative disorder. Levodopa (L-DOPA) remains the gold-standard drug available …

Resveratrol (RES) is a potent antioxidant used for the management of several central
nervous system diseases. RES bioavailability is less than 1 owing to its low solubility and …

Abstract The Blood-Brain Barrier (BBB) significantly impedes drug delivery to the central
nervous system. Nanotechnology, especially surface-functionalized lipid nanoparticles …