Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Cell plasticity in homeostasis and regeneration

B Galliot, L Ghila - Molecular reproduction and development, 2010 - Wiley Online Library
Over the past decades, genetic analyses performed in vertebrate and invertebrate
organisms deciphered numerous cellular and molecular mechanisms deployed during …

[HTML][HTML] Insights into regeneration tool box: An animal model approach

AS Mehta, A Singh - Developmental biology, 2019 - Elsevier
For ages, regeneration has intrigued countless biologists, clinicians, and biomedical
engineers. In recent years, significant progress made in identification and characterization of …

Apoptotic cells provide an unexpected source of Wnt3 signaling to drive hydra head regeneration

S Chera, L Ghila, K Dobretz, Y Wenger, C Bauer… - Developmental cell, 2009 - cell.com
Decapitated Hydra regenerate their heads via morphallaxis, ie, without significant
contributions made by cell proliferation or interstitial stem cells. Indeed, Hydra depleted of …

Caspase-mediated LPS sensing and pyroptosis signaling in Hydra

S Chen, S Li, H Chen, Y Gong, D Yang, Y Zhang… - Science …, 2023 - science.org
Inflammatory caspases sensing lipopolysaccharide (LPS) to drive gasdermin (GSDM)–
mediated pyroptosis is an important immune response mechanism for anti-infection defense …

Autophagy precedes apoptosis during the remodeling of silkworm larval midgut

E Franzetti, ZJ Huang, YX Shi, K Xie, XJ Deng, JP Li… - Apoptosis, 2012 - Springer
Although several features of apoptosis and autophagy have been reported in the larval
organs of Lepidoptera during metamorphosis, solid experimental evidence for autophagy is …

The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in Hydra

MC Vogg, J Ferenc, WC Buzgariu, C Perruchoud… - Science …, 2022 - science.org
The molecular mechanisms that maintain cellular identities and prevent dedifferentiation or
transdifferentiation remain mysterious. However, both processes are transiently used during …

The Hydra model: disclosing an apoptosis-driven generator of Wnt-based regeneration

B Galliot, S Chera - Trends in cell biology, 2010 - cell.com
The Hydra model system is well suited for the eludication of the mechanisms underlying
regeneration in the adult, and an understanding of the core mechanisms is likely to cast light …

Injury‐induced activation of the MAPK/CREB pathway triggers apoptosis‐induced compensatory proliferation in hydra head regeneration

S Chera, L Ghila, Y Wenger… - Development, growth & …, 2011 - Wiley Online Library
After bisection, Hydra polyps regenerate their head from the lower half thanks to a head‐
organizer activity that is rapidly established at the tip. Head regeneration is also highly …

Ecotoxicological assessment of cobalt using Hydra model: ROS, oxidative stress, DNA damage, cell cycle arrest, and apoptosis as mechanisms of toxicity

M Zeeshan, A Murugadas, S Ghaskadbi… - Environmental …, 2017 - Elsevier
The mechanisms underlying cobalt toxicity in aquatic species in general and cnidarians in
particular remain poorly understood. Herein we investigated cobalt toxicity in a Hydra model …