Analysis methods for large-scale neuronal recordings

C Stringer, M Pachitariu - Science, 2024 - science.org
Simultaneous recordings from hundreds or thousands of neurons are becoming routine
because of innovations in instrumentation, molecular tools, and data processing software …

[HTML][HTML] Integrating across behaviors and timescales to understand the neural control of movement

JM Gmaz, JA Keller, JT Dudman, JA Gallego - Current Opinion in …, 2024 - Elsevier
The nervous system evolved to enable navigation throughout the environment in the pursuit
of resources. Evolutionarily newer structures allowed increasingly complex adaptations but …

Population-level coding of avoidance learning in medial prefrontal cortex

B Ehret, R Boehringer, EA Amadei, MR Cervera… - Nature …, 2024 - nature.com
The medial prefrontal cortex (mPFC) has been proposed to link sensory inputs and
behavioral outputs to mediate the execution of learned behaviors. However, how such a link …

Modeling and dissociation of intrinsic and input-driven neural population dynamics underlying behavior

P Vahidi, OG Sani… - Proceedings of the …, 2024 - National Acad Sciences
Neural dynamics can reflect intrinsic dynamics or dynamic inputs, such as sensory inputs or
inputs from other brain regions. To avoid misinterpreting temporally structured inputs as …

MotorNet, a Python toolbox for controlling differentiable biomechanical effectors with artificial neural networks

O Codol, JA Michaels, M Kashefi, JA Pruszynski… - Elife, 2024 - elifesciences.org
Artificial neural networks (ANNs) are a powerful class of computational models for
unravelling neural mechanisms of brain function. However, for neural control of movement …

[HTML][HTML] From innate to instructed: A new look at perceptual decision-making

LT Oesch, MB Ryan, AK Churchland - Current Opinion in Neurobiology, 2024 - Elsevier
Understanding how subjects perceive sensory stimuli in their environment and use this
information to guide appropriate actions is a major challenge in neuroscience. To study …

Decoding the brain: From neural representations to mechanistic models

MW Mathis, AP Rotondo, EF Chang, AS Tolias… - Cell, 2024 - cell.com
A central principle in neuroscience is that neurons within the brain act in concert to produce
perception, cognition, and adaptive behavior. Neurons are organized into specialized brain …

De novo motor learning creates structure in neural activity that shapes adaptation

JC Chang, MG Perich, LE Miller, JA Gallego… - Nature …, 2024 - nature.com
Animals can quickly adapt learned movements to external perturbations, and their existing
motor repertoire likely influences their ease of adaptation. Long-term learning causes lasting …

Speech and music recruit frequency-specific distributed and overlapping cortical networks

N Te Rietmolen, MR Mercier, A Trébuchon, B Morillon… - ELife, 2024 - elifesciences.org
To what extent does speech and music processing rely on domain-specific and domain-
general neural networks? Using whole-brain intracranial EEG recordings in 18 epilepsy …

[HTML][HTML] Nonlinear manifolds underlie neural population activity during behaviour

C Fortunato, J Bennasar-Vázquez, J Park, JC Chang… - bioRxiv, 2023 - ncbi.nlm.nih.gov
There is rich variety in the activity of single neurons recorded during behaviour. Yet, these
diverse single neuron responses can be well described by relatively few patterns of neural …