Abstract The burden of Inflammatory Bowel Disease (IBD) is increasing worldwide, with a
particular increase in the prevalence in the elderly population, due to the ageing of young …

Inflammatory bowel diseases are medically intractable and require constant therapy in many
cases. While a growing number of biologicals and small molecules is available for treatment …

In the ideal world prognostication or predicting disease course in any chronic disease would
allow the clinician to predict disease course, providing crucial information for the patient and …

The intertwined interactions various immune cells have with epithelial cells in our body
require sophisticated experimental approaches to be studied. Due to the limitations of …

This study, utilizing high-throughput technologies and Machine Learning (ML), has identified
gene biomarkers and molecular signatures in Inflammatory Bowel Disease (IBD). We could …

Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative
colitis (UC), are complex and heterogeneous diseases characterized by a multifactorial …

Inflammatory bowel disease (IBD) is a chronic condition affecting the gastrointestinal tract
with an increasing prevalence worldwide (1). It is a complex and multifactorial disorder …

Crohn's disease (CD) is a complex clinical condition characterized by persistent
gastrointestinal inflammation that leads to episodes of flare-ups and subsequent healing …

Background: Infliximab, an anti–tumor necrosis factor monoclonal antibody, has
revolutionized the pharmacological management of immune-mediated inflammatory …

Inflammation is the body's defense response to infection, injury or chemical stimulation.
Chronic inflammation can repeatedly destroy cells and tissues, leading to a variety of human …