Oxidative stress and regeneration

M Jaganjac, L Milkovic, N Zarkovic… - Free Radical Biology and …, 2022 - Elsevier
Regeneration is the process of replacing/restoring a damaged cell/tissue/organ to its full
function and is limited respecting complexity of specific organ structures and the level of …

Repurposing of CNS drugs to treat COVID-19 infection: targeting the sigma-1 receptor

K Hashimoto - European archives of psychiatry and clinical …, 2021 - Springer
The novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The escalating number of SARS-CoV-2-infected …

The sigma-1 receptor as a pluripotent modulator in living systems

TP Su, TC Su, Y Nakamura, SY Tsai - Trends in pharmacological sciences, 2016 - cell.com
The sigma-1 receptor (Sig-1R) is an endoplasmic reticulum (ER) protein that resides
specifically in the mitochondria-associated endoplasmic reticulum (ER) membrane (MAM) …

[HTML][HTML] Neuronal sigma-1 receptors: signaling functions and protective roles in neurodegenerative diseases

DA Ryskamp, S Korban, V Zhemkov… - Frontiers in …, 2019 - frontiersin.org
Sigma-1 receptor (S1R) is a multi-functional, ligand-operated protein situated in
endoplasmic reticulum (ER) membranes and changes in its function and/or expression have …

N, N-dimethyltryptamine (DMT), an endogenous hallucinogen: past, present, and future research to determine its role and function

SA Barker - Frontiers in neuroscience, 2018 - frontiersin.org
This report provides a historical overview of research concerning the endogenous
hallucinogen N, N-dimethyltryptamine (DMT), focusing on data regarding its biosynthesis …

Neuropharmacology of N, N-dimethyltryptamine

TM Carbonaro, MB Gatch - Brain research bulletin, 2016 - Elsevier
Abstract N, N-dimethyltryptamine (DMT) is an indole alkaloid widely found in plants and
animals. It is best known for producing brief and intense psychedelic effects when ingested …

The role of astrocytes in the neurorepair process

RA Chiareli, GA Carvalho, BL Marques… - Frontiers in cell and …, 2021 - frontiersin.org
Astrocytes are highly specialized glial cells responsible for trophic and metabolic support of
neurons. They are associated to ionic homeostasis, the regulation of cerebral blood flow and …

Sigma-1 receptor chaperone at the ER-mitochondrion interface mediates the mitochondrion-ER-nucleus signaling for cellular survival

T Mori, T Hayashi, E Hayashi, TP Su - PloS one, 2013 - journals.plos.org
The membrane of the endoplasmic reticulum (ER) of a cell forms contacts directly with
mitochondria whereby the contact is referred to as the m itochondrion-a ssociated ER m …

Modulation of neural plasticity as a basis for stroke rehabilitation

M Pekna, M Pekny, M Nilsson - Stroke, 2012 - Am Heart Assoc
Current understanding of the mechanisms underlying neural plasticity changes after stroke
stems from experimental models as well as clinical studies and provides the foundation for …

Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction

I Weissberg, L Wood, L Kamintsky, O Vazquez… - Neurobiology of …, 2015 - Elsevier
Post-injury epilepsy (PIE) is a common complication following brain insults, including
ischemic, and traumatic brain injuries. At present, there are no means to identify the patients …