Disseminated metastatic cancer cells represent one of the most relevant causes of disease
relapse and associated death for cancer patients, and a therapeutic target of the highest …

Delayed relapses at distant sites are a common clinical observation for certain types of
cancers after removal of primary tumor, such as breast and prostate cancer. This evidence …

The extracellular matrix (ECM) plays a crucial role in regulating organ homeostasis. It
provides mechanical and biochemical cues directing cellular behaviour and, therefore, has …

Simple Summary A large number of estrogen receptor-positive breast cancer patients show
relapses at the metastatic site up to 20 years after the removal of the primary tumor. This …

Late relapse of disseminated cancer cells is a common feature of some types of tumors.
Several intrinsic and extrinsic factors have been shown to affect reawakening of …