Randall's plaque and calcium oxalate stone formation: role for immunity and inflammation

SR Khan, BK Canales… - Nature Reviews …, 2021 - nature.com
Idiopathic calcium oxalate (CaOx) stones often develop attached to Randall's plaque
present on kidney papillary surfaces. Similar to the plaques formed during vascular …

Effects of fetuin-A with diverse functions and multiple mechanisms on human health

MA Icer, H Yıldıran - Clinical biochemistry, 2021 - Elsevier
Abstract Fetuin-A (Alfa 2-Heremans-Schmid) is a glycoprotein that is mainly synthesized by
hepatocytes and then released into the bloodstream. While fetuin-A, a multifunctional …

[HTML][HTML] Apigenin targets fetuin-A to ameliorate obesity-induced insulin resistance

MC Hsu, CH Chen, MC Wang, WH Chen… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Fetuin-A, a hepatokine secreted by hepatocytes, binds to insulin receptors and consequently
impairs the activation of the insulin signaling pathway, leading to insulin resistance …

Crosstalk between renal and vascular calcium signaling: The link between nephrolithiasis and vascular calcification

CJ Liu, CW Cheng, YS Tsai, HS Huang - International journal of …, 2021 - mdpi.com
Calcium (Ca2+) is an important mediator of multicellular homeostasis and is involved in
several diseases. The interplay among the kidney, bone, intestine, and parathyroid gland in …

[PDF][PDF] Inflammation and injury: what role do they play in the development of Randall's plaques and formation of calcium oxalate kidney stones?

SR Khan - Comptes Rendus. Chimie, 2022 - comptes-rendus.academie-sciences …
Résumé Urinary supersaturation is important for crystallization and likely cause of stone
formation on ductal plugs. Formation of idiopathic stones that develop on Randall's plaques …

Vascular Calcification Is Associated with Fetuin-A and Cortical Bone Porosity in Stone Formers

FG Rodrigues, RFCA Neves, MS Ormanji… - Journal of personalized …, 2022 - mdpi.com
Background: Nephrolithiasis has been associated with bone loss and vascular calcification
(VC), reflecting abnormal extraosseous calcium deposition. Fetuin-A (Fet-A) acts as a potent …

Between a Rock and a Short Place—The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan

IP Heilberg, AB Carvalho, MR Denburg - Current Osteoporosis Reports, 2024 - Springer
Abstract Purpose of Review The impact of nephrolithiasis on skeletal growth and bone
health across the life span of kidney stone formers is reviewed. Main Findings Bone disease …

Kidney diseases: The age of molecular markers

GL da Veiga, B da Costa Aguiar Alves, MM Perez… - Translational …, 2021 - Springer
Kidney diseases are conditions that increase the morbidity and mortality of those afflicted.
Diagnosis of these conditions is based on parameters such as the glomerular filtration rate …

Interaction of fetuin-A with obesity related insulin resistance and diabetes mellitus

Y Öner-İyidoğan, H Koçak - Turkish Journal of Biochemistry, 2024 - degruyter.com
Fetuin-A (FetA) is a glycoprotein primarily synthesized in hepatocytes, but recent studies
have demonstrated that it is also synthesized in adipose tissue, classifying it as both a …

The Association between Aortic Calcification Index and Urinary Stones: A Cross-Sectional Study

W Chen, L Xiong, Q Xu, L Chen, X Huang - Journal of Clinical Medicine, 2022 - mdpi.com
Background: It is believed that vascular calcification and urinary stones may possibly have a
shared mechanism. However, the association between vascular calcification and urinary …