[PDF][PDF] An overview and advancement in ocular drug delivery systems

KS Rathore, RK Nema, SS Sisodia - International Journal of …, 2010 - researchgate.net
Eye is most unique organ of the body. Various drug delivery systems are used to deliver
drug into eyes are used but there are various limitations of conventional systems so …

Formulation and evaluation of sparfloxacin emulsomes-loaded thermosensitive in situ gel for ophthalmic delivery

D Sawant, PM Dandagi, AP Gadad - Journal of sol-gel science and …, 2016 - Springer
The aim of the present study was to develop thermosensitive emulsomal in situ gel for ocular
delivery of sparfloxacin, an antibacterial drug. The study was conducted in two steps. In the …

[PDF][PDF] Impact of sterilisation conditions on the rheological properties of thermoresponsive pluronic F-127-based gels for the ophthalmic use

J Burak, KP Grela, J Pluta, B Karolewicz… - Acta Pol. Pharm …, 2018 - researchgate.net
Sterilisation is a key step in obtaining ophthalmic formulations, such as hydrogels, which
ensure prolonged contact of the active substance with the cornea. In this research Pluronic F …

Fabrication and characterization of timolol maleate and brinzolamide loaded nanostructured lipid carrier system for ocular drug delivery

N Shrivastava, S Khan, S Baboota… - Current Drug Delivery, 2018 - ingentaconnect.com
Background: The combination of timolol maleate (TM) and brinzolamide (BRZ) has potential
therapeutic prospects for treating glaucoma. However, the conventional formulation of TM …

Development and Evaluation of in situ eye gel for delivery of gatifloxacin and betamethasone sodium phosphate

FM Ali, ADH Al-Shohani… - Al Mustansiriyah …, 2025 - ajps.uomustansiriyah.edu.iq
Drug delivery to ocular tissues is challenging due to the rapid removal of instilled drugs due
to the low resident time in ocular tissues. The study aimed to formulate an ophthalmic in situ …

Eye gels for ophthalmic delivery

B McKenzie, G Kay - Expert Review of Ophthalmology, 2015 - Taylor & Francis
The eye's unique physiology, biochemistry and anatomy present the pharmaceutical
scientist with a number of drug delivery problems. Historically, eye drops and eye ointments …

Formulation and development of extended release ocusert for gemifloxacin mesylate with dexamethsaone

SM Keny, K Shah - Research Journal of Pharmacy and …, 2020 - indianjournals.com
Ocular drug delivery is one of the most challenging and fascinating task faced by the
Pharmaceutical Researchers. The challenges to the formulators are to circumvent the …

[PDF][PDF] Newer ophthalmic in situ gel of moxifloxacin hydrochloride: optimization using box behnken statistical design

M Dholakia, R Dave, V Thakkar, H Rana… - International Journal of …, 2018 - academia.edu
Objective: The present research work aims at describing the formulation and evaluation of
the ocular delivery system of moxifloxacin hydrochloride (MH) based on the concept of ion …

[PDF][PDF] AN EXTENSIVE REVIEW ON OPTHALMIC IN SITU GELLING SYSTEM

K Rajeshkumar, G Hariharaputhraayanar - 2023 - wjpr.s3.ap-south-1.amazonaws.com
The current review on in situ gelling systems becomes one of the most popular and
prominent. These eye drops require frequent instillation and cause lachrymal drainage, low …

DESIGN AND OPTIMIZATION OF OCULAR INSERTS FOR PROLONGED DELIVERY OF CIPROFLOXACIN WITH CORTICOSTEROID.

SM Keny, LA Sawaikar, A Savaikar - Indian Drugs, 2024 - search.ebscohost.com
Ocular drug delivery is very challenging and fascinating for pharmaceutical researchers,
especially in the treatment of ocular conjunctivitis. The challenges include delivery of the …