Iron is a critical element for living cells in terrestrial life. Although iron metabolism is strictly
controlled in the body, disturbance of iron homeostasis under certain type of condition leads …

Cellular and stromal components including tumor cells, immune cells, mesenchymal cells,
cancer-linked fibroblasts, and extracellular matrix, constituent tumor microenvironment …

High-grade gliomas, the most common and aggressive primary brain tumors, are
characterized by a complex tumor microenvironment (TME). Among the immune cells …

Cancer cells generally present a higher demand for iron, which plays crucial roles in tumor
progression and metastasis. This iron addiction provides opportunities to develop broad …

Simple Summary In this work, we focused on the synergistic antitumor effects of
photodynamic therapy and ferroptosis. First, we briefly introduced the basic theory of …

With their distinctive physicochemical features, nanoparticles have gained recognition as
effective multifunctional tools for biomedical applications, with designs and compositions …

The immunosuppressive tumor microenvironment (TME) in glioblastoma (GBM) is mainly
driven by tumor‐associated macrophages (TAMs). We explored whether their sustained iron …

The immune function is closely related to iron (Fe) homeostasis and allostasis. The aim of
this bioinformatics-assisted review was twofold;(i) to update the current knowledge of Fe …

Immune cells are essential for initiating and developing the fibrotic process by releasing
cytokines and growth factors that activate fibroblasts and promote extracellular matrix …

The tumor microenvironment (TME) promotes the malignant transformation of cancer cells,
mainly through metabolic reprogramming. As one of the most prominent features of the TME …