Octacosanol and health benefits: Biological functions and mechanisms of action

Y Zhou, F Cao, F Luo, Q Lin - Food Bioscience, 2022 - Elsevier
Octacosanol is a widely distributed natural higher aliphatic alcohol that can be isolated and
purified from rice bran, sugarcane, beeswax, insect wax, etc. Octacosanol exerts various …

Treatment of hypercholesterolemia in NIDDM with policosanol

O Torres, AJ Agramonte, J Illnait, RM Ferreiro… - Diabetes …, 1995 - Am Diabetes Assoc
OBJECTIVE To determine whether elevated levels of cholesterol and low-density lipoprotein
(LDL) cholesterol in non-insulin-dependent diabetes mellitus (NIDDM) patients could be …

Comparative study of policosanol, aspirin and the combination therapy policosanol-aspirin on platelet aggregation in healthy volunteers

ML Arruzazabala, S Valdes, R Mas, D Carbajal… - Pharmacological …, 1997 - Elsevier
A randomized, double-blind, placebo-controlled study was conducted in 43 hea lthy
volunteers to compare the effects of policosanol (20 mg day− 1), aspirin (ASA)(100 mg day …

Effects of policosanol in older patients with type II hypercholesterolemia and high coronary risk

G Castano, R Mas, JC Fernandez… - The Journals of …, 2001 - academic.oup.com
Background. The present study was undertaken to investigate the effects of policosanol in
older patients with type II hypercholesterolemia and more than one concomitant …

Effect of policosanol on platelet aggregation and serum levels of arachidonic acid metabolites in healthy volunteers

D Carbajal, ML Arruzazabala, S Valdes… - … , leukotrienes and essential …, 1998 - Elsevier
Policosanol is a cholesterol-lowering drug with hypocholesterolemic effects demonstrated in
experimental models, healthy volunteers and patients with type II hypercholesterolemia. In …

Carcinogenicity of policosanol in Sprague Dawley rats: a 24 month study

CL Alemán, RM Ferreiro, MN Puig… - Teratogenesis …, 1994 - Wiley Online Library
Abstract The effects of policosanol (50–500 mg/kg) administered orally for 24 months to
Sprague Dawley rats of both sexes were investigated. No differences related to daily clinical …

Carcinogenicity of policosanol in mice: an 18-month study

CL Aleman, MN Puig, EC Elías, CH Ortega… - Food and chemical …, 1995 - Elsevier
Policosanol (trade name Ateromixol) is a new cholesterol-lowering drug that has been
isolated and purified from sugar cane wax. The effects of policosanol (50–500 mg/kg) …

Effect of policosanol in lowering cholesterol levels in patients with type II hypercholesterolemia

E Aneiros, R Más, B Calderon, J Illnait… - Current Therapeutic …, 1995 - Elsevier
A randomized double-blind, placebo-controlled study was conducted in 45 patients with type
II hypercholesterolemia to investigate the efficacy and safety of policosanol administered at …

Policosanol

R Mas - Drugs of the Future, 2000 - access.portico.org
Atherosclerotic vascular diseases, and especially coronary heart disease (CHD), are the
major cause of morbidity and mortality in middle aged and elderly people worldwide (1, 2) …

A comparative study of policosanol versus simvastatin in elderly patients with hypercholesterolemia

G Ortensi, G Julio, V Hector - Current therapeutic research, 1997 - Elsevier
Fifty-three elderly patients (60 to 77 years of age) with primary hypercholesterolemia (total
serum cholesterol⩾ 240 mg/dL) were enrolled in a randomized, double-masked, parallel …