Glucolipotoxicity: a proposed etiology for wooden breast and related myopathies in commercial broiler chickens

JA Lake, B Abasht - Frontiers in physiology, 2020 - frontiersin.org
Wooden breast is one of several myopathies of fast-growing commercial broilers that has
emerged as a consequence of intensive selection practices in the poultry breeding industry …

Revisiting glucose regulation in birds–A negative model of diabetes complications

KL Sweazea - Comparative Biochemistry and Physiology Part B …, 2022 - Elsevier
Birds naturally have blood glucose concentrations that are nearly double levels measured
for mammals of similar body size and studies have shown that birds are resistant to insulin …

Transcriptomic and metabolomic profiling of chicken adipose tissue in response to insulin neutralization and fasting

B Ji, B Ernest, JR Gooding, S Das, AM Saxton, J Simon… - BMC genomics, 2012 - Springer
Background Domestic broiler chickens rapidly accumulate adipose tissue due to intensive
genetic selection for rapid growth and are naturally hyperglycemic and insulin resistant …

Immortalization of chicken preadipocytes by retroviral transduction of chicken TERT and TR

W Wang, T Zhang, C Wu, S Wang, Y Wang, H Li… - PLoS …, 2017 - journals.plos.org
The chicken is an important agricultural animal and model for developmental biology,
immunology and virology. Excess fat accumulation continues to be a serious problem for the …

Broiler chickens (Ross strain) lack insulin-responsive glucose transporter GLUT4 and have GLUT8 cDNA

Y Seki, K Sato, T Kono, H Abe, Y Akiba - General and comparative …, 2003 - Elsevier
Identification of insulin-responsive glucose transporter proteins, GLUT4 and GLUT8, was
attempted in chickens that characteristically are hyperglycemic and insulin resistant …

Identification of selection signatures involved in performance traits in a paternal broiler line

OAC Almeida, GCM Moreira, FM Rezende… - BMC genomics, 2019 - Springer
Background Natural and artificial selection leads to changes in certain regions of the
genome resulting in selection signatures that can reveal genes associated with the selected …

Characterisation of glucose transporter (GLUT) gene expression in broiler chickens

T Kono, M Nishida, Y Nishiki, Y Seki, K Sato… - British Poultry …, 2005 - Taylor & Francis
1. Glucose transporter (GLUT) proteins, one of which is the major insulin-responsive
transporter GLUT4, play a crucial role in cellular glucose uptake and glucose homeostasis in …

Branched‐chain amino acids modulate the expression of hepatic fatty acid metabolism‐related genes in female broiler chickens

J Bai, E Greene, W Li, MT Kidd… - Molecular nutrition & food …, 2015 - Wiley Online Library
Scope The effects and roles of branched‐chain amino acids (BCAAs) in hepatic fat
metabolism are still unknown. Methods and results Here, we used broiler chickens, in which …

Is visfatin an adipokine or myokine? Evidence for greater visfatin expression in skeletal muscle than visceral fat in chickens

SM Krzysik-Walker, OM Ocón-Grove… - …, 2008 - academic.oup.com
Visfatin, an adipokine hormone produced primarily by visceral adipose tissue in mammals,
has been implicated in the immune system, cellular aging, and glucose metabolism …

Orexin system is expressed in avian muscle cells and regulates mitochondrial dynamics

K Lassiter, E Greene, A Piekarski… - American Journal …, 2015 - journals.physiology.org
Orexin A and B, orexigenic peptides produced primarily by the lateral hypothalamus that
signal through two G protein-coupled receptors, orexin receptors 1/2, have been implicated …