Summary July 20, 2021 marked the 30th anniversary of the publication of the landmark trial
by the British Medical Research Council showing unequivocally that maternal intake of folic …

Folates have a pterine core structure and high metabolic activity due to their ability to accept
electrons and react with O-, S-, N-, C-bounds. Folates play a role as cofactors in essential …

Recent findings point toward diet having a major impact on human health. Diets can either
affect the gut microbiota resulting in alterations in the host's physiological responses or by …

Many of the scientific and regulatory challenges that exist in research on the safety, quality
and efficacy of dietary supplements are common to all countries as the marketplace for them …

For three decades, the US Public Health Service has recommended that all persons capable
of becoming pregnant consume 400 μg/day of folic acid (FA) to prevent neural tube defects …

This is the fifth in the series of reviews developed as part of the Biomarkers of Nutrition for
Development (BOND) program. The BOND Iron Expert Panel (I-EP) reviewed the extant …

Folate, an essential nutrient found naturally in foods in a reduced form, is present in dietary
supplements and fortified foods in an oxidized synthetic form (folic acid). There is …

This report on vitamin B-12 (B12) is part of the Biomarkers of Nutrition for Development
(BOND) Project, which provides state-of-the art information and advice on the selection, use …

Background It has been reported that neural tube defects (NTD) can be prevented with
periconceptional folic acid supplementation. The effects of different doses, forms and …

Human nutrition is a branch of medicine based on foods biochemical interactions with the
human body. The phenotypic transition from health to disease status can be attributed to …