Multicomponent reactions (MCRs) are composed of three or more reagents in which the final
product has all or most of the carbon atoms from its starting materials. These reactions …

The formation of canonical base pairs through Watson–Crick hydrogen bonding sits at the
heart of the genetic apparatus. The specificity of the base pairing of adenine with …

To guide the design of alternative genetic systems, we measured melting temperatures of
DNA duplexes containing matched and mismatched nucleobase pairs from natural and …

This report summarizes the content of the author's lecture given at the 9th ISSOL Conference
on theOrigin of Life'in Oaxaca on 2 July 2002*. The report consists of introductory remarks …

Natural nucleic acids duplexes formed by Watson–Crick base pairing fold into right‐handed
helices that are classified in two families of secondary structures, ie the A‐and B‐form. For a …

Planarizable push–pull flipper probes have been introduced to image order and tension of
membranes in living cells. In this report, we show that fluorescent flippers can also be …

During evolution ribose was selected as the exclusive sugar component of nucleic acids.
The selection is explained by using molecular models and by eliminating most of the other …

The multicomponent reaction (MCR) is an important research field in the organic synthetic
methodology. In 1956, Professor Friedrich Asinger reported a method for synthesizing …

Assuming that the efficiency of the incorporation of 5-methyl-2′-deoxyisocytosine-5′
triphosphate (dMiCTP) and dTTP opposite isoguanine (iG) is a measure of the proportion of …

The diversity of backbone modifications in the study of primitive informational polymers is
partly limited by the plausible formation of their prebiotic starting components. In this paper …