Introduction: Chronic rhinosinusitis with nasal polyps (CRSwNP) affects 1–2.5% of the
population and is associated with significant adverse effects on quality of life (QoL) …

The recent classification of chronic rhinosinusitis (CRS) focusses on investigating underlying
immunopathophysiological mechanisms. Primary CRS is subdivided based on endotype …

Background The availability of data generated from different sources is increasing with the
possibility to link these data sources with each other. However, linked administrative data …

Introduction: Chronic rhinosinusitis is a common condition characterized by inflammation of
the nasal and sinus linings, rhinorrhea, nasal blockage, facial pain, and loss of sense of …

Various chronic inflammatory airway diseases can be treated with low-dose, long-term
(LDLT) macrolide therapy. LDLT macrolides can be one of the therapeutic options for …

Background: Chronic eosinophilic rhinosinusitis with nasal polyps (CRSwNP eosinophilic) is
characterised by the formation of benign and bilateral nasal polyps. We aimed to compare …

We look back at the end of what soon will be seen as an historic year, from COVID-19 to real-
world introduction of biologicals influencing the life of our patients. This review describes the …

Nirmatrelvir/ritonavir (PAXLOVIDTM, Pfizer) is an anti-infective inhibiting CYP3A4 indicated
for the treatment of COVID-19 in adults at increased risk of severe COVID-19. As a newly …

Objectives Chronic rhinosinusitis (CRS) symptoms are experienced by an estimated 11% of
UK adults, and symptoms have major impacts on quality of life. Data from UK and elsewhere …

Objective Macrolide antibiotics are often used to prevent infection and inflammation after
functional endoscopic sinus surgery for the treatment of chronic rhinosinusitis (CRS). The …